1134448-90-0Relevant academic research and scientific papers
Synthesis of chaetomellic anhydride A, A potent inhibitor of ras protein farnesyltransferase
Yoshimitsu, Takehiko,Arano, Yoshimasa,Kaji, Tomohiro,Ino, Tatsunori,Nagaoka, Hiroto,Tanaka, Tetsuaki
, p. 179 - 186 (2009)
Chaetomellic anhydride A, a potent inhibitor of Ras protein farnesyltransferase, was synthesized in 61% yield over four steps from methyl propionate. The synthesis features palladium-catalyzed carboxylation reaction under Cacchi conditions, efficiently in
