1134583-99-5Relevant articles and documents
Relationships between the structure of 6-substituted 6,8-diazabicyclo[3.2.2]nonan-2-ones and their σ receptor affinity and cytotoxic activity
Holl, Ralph,Schepmann, Dirk,Bednarski, Patrick J.,Gruenert, Renate,Wuensch, Bernhard
, p. 1445 - 1455 (2009)
A series of 2-oxo-6,8-diazabicyclo[3.2.2]nonane derivatives was prepared and the affinity towards σ1 and σ2 receptors was investigated by means of radioligand binding assays as well as their inhibition of the growth of six human tumo