113473-13-5Relevant articles and documents
Asymmetric dihydroxylation of acrolein acetals: Synthesis of stable equivalents of Enantiopure glyceraldehyde and glycidaldehyde
Oi, Ryu,Sharpless, K. Barry
, p. 2095 - 2098 (1992)
Asymmetric dihydroxylation (ADH) of acrolein acetals afforded optically active glyceraldehyde equivalents. Enantiopure 3-(1,2-dihydroxyethyl)-1,5-dihydro-3H-2,4-benzodioxepine 3, a protected glyceraldehyde, was obtained from the corresponding acrolein acetal 2 by ADH and subsequent recrystallization. Enantiopure 3-(1,2-epoxyethyl)-1,5-dihydro-3H-2,4-benzodioxepine 5, a protected glycidaldehyde, was produced in two steps from 3.