113474-05-8Relevant articles and documents
New Synthesis of the Corticosterone Side-Chain
Solyom, Sandor,Szilagyi, Katalin,Toldy, Lajos
, p. 153 - 160 (2007/10/02)
Condensation reactions between azlactone 2 and 17-ketosteroids 1 followed by opening of the azlactone ring with sodium methanolate yields methyl 20-benzoylamino-17(20)-pregnen-21-oates 6.Reduction of the ester and subsequent hydrolysis produce compounds with the corticosterone side-chain as well as a ring-closed product of new type.