113474-68-3

Basic information

• Product Name: (PR,3R,4R,P'R)-1-(tert-butoxycarbonyl)-3,4-bis(methylphenylphosphino)pyrrolidine
• CAS NO: 113474-68-3
• Molecular Weight: 415.452
• Mol File: 113474-68-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (PR,3R,4R,P'R)-1-(tert-butoxycarbonyl)-3,4-bis(methylphenylphosphino)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (PR,3R,4R,P'R)-1-(tert-butoxycarbonyl)-3,4-bis(methylphenylphosphino)pyrrolidine(113474-68-3)
• EPA Substance Registry System: (PR,3R,4R,P'R)-1-(tert-butoxycarbonyl)-3,4-bis(methylphenylphosphino)pyrrolidine(113474-68-3)

Safety Data

• Hazardous Substances Data: 113474-68-3(Hazardous Substances Data)

Upstream product

• 113452-35-0 {(PS,3R,4R,P'S)-1-(tert-butoxycarbonyl)-3,4-bis(methylphenylphosphino)pyrrolidine-P,P'}diiodopalladium 
• 113452-24-7 -1-(tert-Butoxycarbonyl)-3,4-bis-(methylphenylphosphino)pyrrolidin 
• 113452-08-7 -3,4-Bis(phenylphosphanyl)pyrrolidinium hydrochloride 
• 99135-90-7 (3R,4R)-3,4-bis(diphenylphosphanyl)pyrrolidine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 113452-24-7 (PS,3R,4R,P'S)-1-(tert-Butoxycarbonyl)-3,4-bis-(methylphenylphosphino)pyrrolidin 
• 113452-25-8 (PR,3R,4R,P'S)-1-(tert-Butoxycarbonyl)-3,4-bis-(methylphenylphosphino)pyrrolidin 
• 5259-72-3 cyclo-octa-1,5-diene 

Relevant articles and documents

Enantioselective Catalysis, 5. - New Ligands with Four Stereogenic Centers. Synthesis and Separation of the Three Diastereomeric -3,4-Bis(methylphenylphosphino)-pyrrolidines

From (3R,4R)-3,4-bis(diphenylphosphino)pyrrolidine (1a) or the N-benzyl derivative 1b -3,4-bis(phenylphosphino)pyrrolidine (2a-*) resp. its N-benzyl derivative 2b-* were prepared as diastereomeric mixture.From 2a-* isomerically pure (PR,3R,4R,P'S)-3,4-bis(benzylphenylphosphino)pyrrolidine (3a-3) was prepared. -3,4-bis(methylphenylphosphino)pyrrolidine (4a-*), obtained from 2a-*, was a mixture of the three possible diastereomers.This mixture could be separated through the palladium complexes of the N-tert-butoxycarbonyl derivatives 8c-*. diiodopalladium(II) (8c-1) and for comparison (1,5-cyclooctadiene)rhodium-(I) tetrafluoroborate (11) were characterised by X-ray crystallography.