1134776-30-9

Basic information

• Product Name: 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid
• Synonyms: 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid;(R)-4-(1-((tert-butoxycarbonyl)aMino)ethyl)benzoic acid;(R)-4-(1-Boc-amino-ethyl)-benzoic acid
• CAS NO: 1134776-30-9
• Molecular Formula: C₁₄H₁₉NO₄
• Molecular Weight: 265.30496
• Mol File: 1134776-30-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.151
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid(1134776-30-9)
• EPA Substance Registry System: 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid(1134776-30-9)

Safety Data

• Hazardous Substances Data: 1134776-30-9(Hazardous Substances Data)

Usage

General Description

4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid is a chemical compound with the molecular formula C18H25NO4. It is a derivative of benzoic acid and contains a tert-butoxycarbonyl (Boc) protecting group on the amino group. 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid is used in the synthesis of pharmaceuticals and as a building block for the preparation of various organic molecules. It is also used in peptide chemistry as a protecting group for amino acids. 4-[(1R)-1-[[(tert-Butoxy)carbonyl]amino]ethyl]benzoic acid has potential applications in the field of medicine and drug development due to its structural properties and functionality.

Upstream product

• 578729-21-2 [(R)-1-(4-bromo-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 124-38-9 carbon dioxide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 24358-62-1 (R)-1-(4-bromophenyl)ethylamine 
• 1021491-25-7 (R)-4-(1-tert-butoxycarbonylaminoethyl)benzoic acid methyl ester 

Downstream Products

• 1134776-31-0 (R)-{1-[4-(2,5-cis/trans-dimethylpyrrolidine-1-carbonyl)phenyl]ethyl}carbamic acid tert-butyl ester 
• 1097196-96-7 (1R)-1-[4-(methoxycarbonyl)phenyl]ethanaminium chloride 

Relevant articles and documents

Functionalized Chiral Bambusurils: Synthesis and Host-Guest Interactions with Chiral Carboxylates

Bambusurils are a class of macrocyclic anion receptors that exhibit notable anion recognition properties, able to bind various inorganic anions as well the carboxylates or sulfonates. Recently, we reported enantioselective recognition of chiral carboxylates using non-functionalized chiral bambusuril derivatives. Herein, we report the synthesis and host-guest properties of two new representatives of chiral bambusuril macrocycles bearing ester functional groups, differing by the substituents attached to their portals. Their supramolecular properties in terms of carboxylate binding were studied by means of NMR in DMSO-d6. The reported bambusurils bind selected chiral carboxylates with enantioselectivity factors up to 3.1. The results indicated that the selectivity towards different carboxylates is governed by the steric constraint of the substituents surrounding bambusuril portals. No clear trend in the binding affinities and their enantioselectivities was found.