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1134782-21-0

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1134782-21-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1134782-21-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,4,7,8 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1134782-21:
(9*1)+(8*1)+(7*3)+(6*4)+(5*7)+(4*8)+(3*2)+(2*2)+(1*1)=140
140 % 10 = 0
So 1134782-21-0 is a valid CAS Registry Number.

1134782-21-0Relevant articles and documents

Synthesis of fluorinated analogues of the neurosteroid GABAA receptor antagonist, 17-PA

Deniau, Gildas,Sillar, Keith T.,O'Hagan, David

experimental part, p. 881 - 887 (2009/04/06)

The steroid 17-PA is a GABAA receptor antagonist which is finding use as a tool in evaluating agonistic/antagonistic activity at GABAA receptors. Compounds with improved efficacy over 17-PA would be are advantageous for such studies. Accordingly a series of novel analogues of the neurosteroid 17-PA have been prepared and a convenient two-step route is presented which is amenable to the synthesis of analogues with electron-donating para-aromatic substituents including fluorine. However, for the meta-fluoro analogue then the original four-step route to 17-PA remains more efficient overall. The paper describes these syntheses and discusses the electronic factors which influence this synthetic chemistry.

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