([ring-D5]Phe3)-Octreotide is a synthetic analog of the hormone somatostatin, characterized by its cyclic octapeptide structure and increased potency compared to the natural hormone. This analog achieves enhanced stability and longer duration of action through the substitution of a deuterated phenylalanine at position 3, which also contributes to its improved pharmacokinetic properties.
1134880-79-7
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Basic information
- Product Name: ([ring-D5]Phe3)-Octreotide
- Synonyms: ([ring-D5]Phe3)-Octreotide;([ring-D5]Phe3)-SMS-201-995, (D-Phe5,Cys6·11,[ring-D5]Phe7,D-Trp8,L-Threoninol12)-SoMatostatin-14 (5-12);H-D-Phe-Cys-[ring-D5]Phe-D-Trp-Lys-Thr-Cys-L-threoninol
- CAS NO:1134880-79-7
- Molecular Formula: C49H61D5N10O10S2
- Molecular Weight: 1024.27014889
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1134880-79-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: ([ring-D5]Phe3)-Octreotide(CAS DataBase Reference)
- NIST Chemistry Reference: ([ring-D5]Phe3)-Octreotide(1134880-79-7)
- EPA Substance Registry System: ([ring-D5]Phe3)-Octreotide(1134880-79-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1134880-79-7(Hazardous Substances Data)
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1134880-79-7 Usage
Uses
Used in Oncology:([ring-D5]Phe3)-Octreotide is utilized as an anti-tumor agent for the treatment of specific tumor types, including carcinoid, gastrinoma, and VIPomas. It functions by binding to somatostatin receptors on tumor cells, thereby inhibiting the release of hormones that promote growth and reducing the rate of tumor progression. This targeted approach helps in controlling symptoms and slowing the advancement of the disease in affected patients.
Check Digit Verification of cas no
The CAS Registry Mumber 1134880-79-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,4,8,8 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.Calculate Digit Verification of CAS Registry Number 1134880-79:
(9*1)+(8*1)+(7*3)+(6*4)+(5*8)+(4*8)+(3*0)+(2*7)+(1*9)=157
157 % 10 = 7
So 1134880-79-7 is a valid CAS Registry Number.
1134880-79-7Upstream product
1134880-79-7Downstream Products
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([ring-D5]Phe3)-Octreotide
