1135031-46-7

Basic information

• Product Name: (4E)-5-[4-(benzyloxy)-3-methylquinolin-2-yl]penten-1-ol
• Synonyms: (4E)-5-[4-(benzyloxy)-3-methylquinolin-2-yl]penten-1-ol
• CAS NO: 1135031-46-7
• Molecular Weight: 333.43
• Mol File: 1135031-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4E)-5-[4-(benzyloxy)-3-methylquinolin-2-yl]penten-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (4E)-5-[4-(benzyloxy)-3-methylquinolin-2-yl]penten-1-ol(1135031-46-7)
• EPA Substance Registry System: (4E)-5-[4-(benzyloxy)-3-methylquinolin-2-yl]penten-1-ol(1135031-46-7)

Safety Data

• Hazardous Substances Data: 1135031-46-7(Hazardous Substances Data)

Upstream product

• 356761-10-9 4-(benzyloxy)-2-(chloromethyl)-3-methylquinoline 
• 5371-52-8 2-hydroxytetrahydrofuran 
• 1135031-03-6 diethyl {[4-(benzyloxy)-3-methylquinolin-2-yl]methyl}phosphonate 

Relevant articles and documents

QUINOLONE DERIVATIVE

As a result of extensive studies on NAD(P)H oxidase inhibitors, the present inventors found that a quinolone derivative having, at the 2-position, an alkyl group substituted with a heteroatom or the like has an excellent NAD(P)H oxidase inhibitory activity, and accomplished the present invention. The compound of the present invention has a reactive oxygen species production inhibitory activity based on the NAD(P)H oxidase inhibitory activity, and therefore can be used as an agent for preventing and/or treating diabetes, impaired glucose tolerance, hyperlipidemia, fatty liver, diabetetic complications and the like.