1135032-38-0

Basic information

• Product Name: 4-(benzyloxy)-2-[(4-hexanoylpiperazin-1-yl)methyl]-3-methylquinoline
• Synonyms: 4-(benzyloxy)-2-[(4-hexanoylpiperazin-1-yl)methyl]-3-methylquinoline
• CAS NO: 1135032-38-0
• Molecular Weight: 445.605
• Mol File: 1135032-38-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(benzyloxy)-2-[(4-hexanoylpiperazin-1-yl)methyl]-3-methylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2-[(4-hexanoylpiperazin-1-yl)methyl]-3-methylquinoline(1135032-38-0)
• EPA Substance Registry System: 4-(benzyloxy)-2-[(4-hexanoylpiperazin-1-yl)methyl]-3-methylquinoline(1135032-38-0)

Safety Data

• Hazardous Substances Data: 1135032-38-0(Hazardous Substances Data)

Upstream product

• 18903-05-4 1-hexanoylpiperazine 
• 356761-10-9 4-(benzyloxy)-2-(chloromethyl)-3-methylquinoline 

Relevant articles and documents

QUINOLONE DERIVATIVE

As a result of extensive studies on NAD(P)H oxidase inhibitors, the present inventors found that a quinolone derivative having, at the 2-position, an alkyl group substituted with a heteroatom or the like has an excellent NAD(P)H oxidase inhibitory activity, and accomplished the present invention. The compound of the present invention has a reactive oxygen species production inhibitory activity based on the NAD(P)H oxidase inhibitory activity, and therefore can be used as an agent for preventing and/or treating diabetes, impaired glucose tolerance, hyperlipidemia, fatty liver, diabetetic complications and the like.