113520-36-8

Basic information

• Product Name: 1,4-Phenylenediacetic Acid Ethyl Ester
• Synonyms: 1,4-Phenylenediacetic Acid Ethyl Ester
• CAS NO: 113520-36-8
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.23716
• Mol File: 113520-36-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 1,4-Phenylenediacetic Acid Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Phenylenediacetic Acid Ethyl Ester(113520-36-8)
• EPA Substance Registry System: 1,4-Phenylenediacetic Acid Ethyl Ester(113520-36-8)

Safety Data

• Hazardous Substances Data: 113520-36-8(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

1,4-Phenylenediacetic Acid Eethyl Ester is an arendiacetic ester used in the preparation of potent β-3 receptor agonist.

Upstream product

• 64-17-5 ethanol 
• 7325-46-4 1,4-phenylenediacetic acid 
• 36076-26-3 diethyl 2,2'-(1,4-phenylene)diacetate 

Downstream Products

• 43153-12-4 ethyl 2-(4-formylphenyl)acetate 
• 861448-74-0 [4-(2-hydroxy-2-methylpropyl)phenyl]acetic acid 

Relevant articles and documents

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The invention relates to a compound with AMPK agonistic activity and a prodrug thereof, and as well as a preparation method and medical application of a prodrug thereof. The compound has the structure shown in the formula (I), and the prodrug of the compound has the structure shown in the formula (II), wherein each group and the substituent are as defined in the specification. The invention discloses a preparation method of the compound and application of the compound in prevention and treatment AMPK related diseases, and the AMPK related diseases include, but are not limited to, energy metabolism abnormality related diseases. Neurodegenerative diseases and inflammation-related diseases and the like.

Sulfonamide derivatives for the treatment of diseases

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