1135312-23-0

Basic information

• Product Name: 2,2,2-trifluoro-1-(2'-fluorophenyl)ethyl isobutyrate
• CAS NO: 1135312-23-0
• Molecular Weight: 264.22
• Mol File: 1135312-23-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2,2-trifluoro-1-(2'-fluorophenyl)ethyl isobutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-1-(2'-fluorophenyl)ethyl isobutyrate(1135312-23-0)
• EPA Substance Registry System: 2,2,2-trifluoro-1-(2'-fluorophenyl)ethyl isobutyrate(1135312-23-0)

Safety Data

• Hazardous Substances Data: 1135312-23-0(Hazardous Substances Data)

Upstream product

• 97-72-3 2-Methylpropionic anhydride 
• 124004-74-6 α-(trifluoromethyl)-2-fluorobenzenemethanol 

Relevant articles and documents

Nonenzymatic kinetic resolution of racemic 2,2,2-trifluoro-1-aryl ethanol via enantioselective acylation

Kinetic resolution of a series of 2,2,2-trifluoro-1-aryl ethanol with (R)-benzotetramisole as the catalyst has been investigated. The result showed that when the aryl group in the substrate was a phenyl (or a phenyl substituted by an electron-donating group) or a naphthyl (an extended phenyl) group, the system could give an s value higher than 20. Preparative KR examples demonstrated the applicability of this method in the preparation of some of enantiomerically pure 2,2,2-trifluoro-1-aryl ethanol or 2,2,2-trifluoro-1-aryl-ethyl iso-butyrate.