113565-15-4Relevant articles and documents
Comprehensive Synthetic Route to Eight Diastereomeric Podophyllum Lignans
Forsey, Steven P.,Rajapaksa, Dayananda,Taylor, Nicholas J.,Rodrigo, Russell
, p. 4280 - 4290 (2007/10/02)
An oxabicyclo compound, 9, prepared in 47percent yield through an isobenzofuran intermediate was converted with excellent regio- and stereocontrol to eight (+/-)-lignan lactones of the podophyllotoxin series.One of the eight, epiisopicropodophyllin, 36, t
TOTAL SYNTHESIS OF (+/-)-PODOPHYLLOTOXIN AND (+/-)-EPIPODOPHYLLOTOXIN.
Eycken, J. Van der,Clercq, P. De,Vandewalle, M.
, p. 3871 - 3874 (2007/10/02)
A novel approach to (+/-)-epipodophyllotoxin (2) and hence also (+/-)-podophyllotoxin (1) is described, involving as a key-step the stereoselective ring closure of the TMS-ester derived from 14a to the tetralin derivative 15 with mesyl chloride.
A stereocontrolled synthesis of antineoplastic podophyllum lignans
Rajapaksa,Rodrigo
, p. 6208 - 6209 (2007/10/02)
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