1135867-81-0

Basic information

• Product Name: N-(hex-5-en-1-yl)-4-methylaniline
• Synonyms: N-(hex-5-en-1-yl)-4-methylaniline
• CAS NO: 1135867-81-0
• Molecular Weight: 189.301
• Mol File: 1135867-81-0.mol

Chemical Properties

• CAS DataBase Reference: N-(hex-5-en-1-yl)-4-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(hex-5-en-1-yl)-4-methylaniline(1135867-81-0)
• EPA Substance Registry System: N-(hex-5-en-1-yl)-4-methylaniline(1135867-81-0)

Safety Data

• Hazardous Substances Data: 1135867-81-0(Hazardous Substances Data)

Upstream product

• 34825-70-2 hex-5-en-1-amine 
• 106-38-7 para-bromotoluene 
• 106-49-0 p-toluidine 
• 2695-47-8 6-Bromo-1-hexene 
• 1119-60-4 hept-6-enoic acid 

Downstream Products

• 1135867-83-2 4-methyl-N-(2-methylcyclopentyl)aniline 

Relevant articles and documents

Visible-Light-Enabled Direct Decarboxylative N-Alkylation

The development of efficient and selective C?N bond-forming reactions from abundant feedstock chemicals remains a central theme in organic chemistry owing to the key roles of amines in synthesis, drug discovery, and materials science. Herein, we present a dual catalytic system for the N-alkylation of diverse aromatic carbocyclic and heterocyclic amines directly with carboxylic acids, by-passing their preactivation as redox-active esters. The reaction, which is enabled by visible-light-driven, acridine-catalyzed decarboxylation, provides access to N-alkylated secondary and tertiary anilines and N-heterocycles. Additional examples, including double alkylation, the installation of metabolically robust deuterated methyl groups, and tandem ring formation, further demonstrate the potential of the direct decarboxylative alkylation (DDA) reaction.

Aerobic intramolecular aminothiocyanation of unactivated alkenes promoted by in situ generated iodine thiocyanate

Aerobic intramolecular aminothiocyanation of unactivated alkenes has been developed by in situ generated iodine thiocyanate under open-flask conditions. This protocol provides a concise and efficient method for synthesizing SCN-containing pyrrolidine, piperidine and indoline derivatives with isolated yields of up to 87%. Furthermore, mixing iodine and sodium thiocyanate with oxygen afforded iodine thiocyanate (ISCN) and dithiocyanatoiodate [I(SCN)2]- which were testified by liquid chromatography mass spectrometry. A mechanistic investigation indicates that iodonium ion and sulfonium ion intermediates might be involved in this transformation.

An Aminopyridinato Titanium Catalyst for the Intramolecular Hydroaminoalkylation of Secondary Aminoalkenes

The easily accessible 2-(methylamino)pyridinato titanium complex initially synthesized by Kempe is used as catalyst for efficient intramolecular hydroaminoalkylation reactions of secondary aminoalkenes. The corresponding reactions of N-aryl-substituted 1-aminohept-6-enes and 1-aminohex-5-enes directly give access to 2-methylcyclohexyl- or 2-methylcyclopentylamines in good yields. In addition, intramolecular hydroaminoalkylations of an N-alkyl-substituted secondary aminoalkene and a geminally β-disubstituted substrate are described for the first time. While all products are formed as mixtures of two diastereoisomers, better trans/cis ratios are observed during the formation of 2-methylcylopentylamines.