113598-55-3Relevant academic research and scientific papers
Building Congested Ketone: Substituted Hantzsch Ester and Nitrile as Alkylation Reagents in Photoredox Catalysis
Chen, Wenxin,Liu, Zheng,Tian, Jiaqi,Li, Jin,Ma, Jing,Cheng, Xu,Li, Guigen
supporting information, p. 12312 - 12315 (2016/10/07)
For the first time, 4-alkyl Hantzsch esters were used to construct molecules with all-carbon quaternary centers by visible light-induced photoredox catalysis via transfer alkylation. Up to a 1500 h-1 turnover frequency was achieved in this reaction. Reactions of 4-alkyl Hantzsch nitriles as tertiary radical donors joined two contiguous all-carbon quaternary centers intermolecularly, and this chemistry was used to synthesize a common precursor of a class of hydroxysteroid dehydrogenase inhibitors.
Reaction of 3-Amino-2-alkenimines with Alkali Metals: Unexpected Synthesis of Substituted 4-(Arylamino)quinolines
Barluenga, Jose,Aguilar, Enrique,Joglar, Jesus,Olano, Bernardo,Fustero, Santos
, p. 2596 - 2598 (2007/10/02)
A study of the reduction of 3-amino-2-alkenimines 1 with alkali metals is reported.The nature of the alkali metal plays an important role in the course of the process.In this context, a new and simple method for the regioselective synthesis of 4-(arylamino)quinolines 4 from 1 and sodium or potassium is described.
Mild and Regiospecific Reduction of Masked 1,3-Dicarbonyl Derivatives to Monocarbonyl Compounds and Primary and Secodary Amines
Barluenga, Jose,Aguilar, Enrique,Olano, Bernardo,Fustero, Santos
, p. 1741 - 1744 (2007/10/02)
The regiospecific reduction of masked 1,3-dicarbonyl compounds to the corresponding saturated monocarbonyl 3 or iminic 4 compounds via 3-amino-2-alkenimines 1 is described.The formation of 3 and 4 can be explained in terms of a double reduction process from 1.A simple method for the synthesis of primary and secondary amines 6 is also described.
