113602-63-4

Upstream product

• 65171-92-8 ethyl 3-hydroxy-1-phenyl-1H-pyrrole-2-carboxylate 

Downstream Products

• 113602-67-8 ethyl 4,5-dibromo-3-(1-methylethoxy)-1-phenyl-1H-pyrrole-2-carboxylate 
• 113589-12-1 4,5-dibromo-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H-pyrrole-2-carboxamide 
• 113602-71-4 4,5-dibromo-3-(1-methylethoxy)-1-phenyl-1 H-pyrrole-2-carboxylic acid 

Relevant academic research and scientific papers

Novel thiophene-, pyrrole-, furan-, and benzenecarboxyamidotetrazoles as potential antiallergy agents

The synthesis and antiallergic activity of a series of novel thiophene-, pyrrole-, furan-, and benzenecarboxamidototrazoles are described. A number of compounds inhibit the release of histamine from anti-IgE-stimulated human basophils. Optimal inhibition

N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof

The present invention is for compounds having the formula of N-1H-tetrazol-5-yl-2-thiophenecarboxamides, N-1H-tetrazol-5-yl-2-pyrrolecarboxamides, N-1H-tetrazol-5-yl-2-furancarboxamides or analogs of each of the carboxamides. The compounds are useful for the treatment of allergic or inflammatory conditions or diseases. Thus, pharmaceutical compositions and methods of use are also the invention. Processes of preparation for the compounds are also the invention.