1136499-06-3

Basic information

• Product Name: (R)-(-)-3-aminomethyl-5-methylhexanoic acid (-)-(O,O')-di-p-toluoyl-D-tartaric acid salt
• CAS NO: 1136499-06-3
• Molecular Weight: 545.587
• Mol File: 1136499-06-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(-)-3-aminomethyl-5-methylhexanoic acid (-)-(O,O')-di-p-toluoyl-D-tartaric acid salt(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-3-aminomethyl-5-methylhexanoic acid (-)-(O,O')-di-p-toluoyl-D-tartaric acid salt(1136499-06-3)
• EPA Substance Registry System: (R)-(-)-3-aminomethyl-5-methylhexanoic acid (-)-(O,O')-di-p-toluoyl-D-tartaric acid salt(1136499-06-3)

Safety Data

• Hazardous Substances Data: 1136499-06-3(Hazardous Substances Data)

Upstream product

• 32634-68-7 (2S,3S)-di-4-toluoyltartaric acid 
• 128013-69-4 (R,S)-3-iso-butyl-4-aminobutyric acid 

Relevant articles and documents

NOVEL RESOLUTION PROCESS FOR PREGABALIN

Present invention relates to a novel and improved process for the resolution of racemic pregabalin of formula (I) into (S)-(+)-pregabalin [(S)-(+)-3-aminomethyl-5-methylhexanoic acid] of formula (III) via the novel acid addition salt [(S)-(+) 3-aminomethyl-5-methylhexanoic acid, (-)-O, O'-di-p-toluoyl-L-tartaric acid salt] of formula (II). (S)-(+)-pregabalin of formula-III has analgesic, anticonvulsant and anxiolytic properties and hence is of great therapeutic significance.