113660-19-8

Basic information

• Product Name: Benzamide, N,N'-[oxybis(methylene)]bis-
• CAS NO: 113660-19-8
• Molecular Formula: C16H16N2O3
• Molecular Weight: 284.315
• Mol File: 113660-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N'-[oxybis(methylene)]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N'-[oxybis(methylene)]bis-(113660-19-8)
• EPA Substance Registry System: Benzamide, N,N'-[oxybis(methylene)]bis-(113660-19-8)

Safety Data

• Hazardous Substances Data: 113660-19-8(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 55-21-0 benzamide 

Relevant articles and documents

Mechanism of Hydrolysis of Benzamidomethyl Derivatives of Phenols and Its Implications for Prodrug Design

A series of O-benzamidomethyl derivatives of phenols was synthesized, and their rates of hydrolysis were investigated.The hydrolyses of the compounds follow pseudo-first-order kinetics resulting in quantitative and rapid regeneration of the phenol.The rates of hydrolysis were shown to be dependent on phenol nucleofugicity as well as the pKa of the amide.The mechanism of hydrolysis apparently involves as elimination of the phenol anion from the conjugate base of the amide (E1cB-like).