113660-41-6

Basic information

• Product Name: ethyl 3-(1-methyl-1H-indol-3-yl)acrylate
• Synonyms: ethyl 3-(1-methyl-1H-indol-3-yl)acrylate
• CAS NO: 113660-41-6
• Molecular Formula: C₁₄H₁₅NO₂
• Molecular Weight: 229.2744
• Mol File: 113660-41-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 3-(1-methyl-1H-indol-3-yl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(1-methyl-1H-indol-3-yl)acrylate(113660-41-6)
• EPA Substance Registry System: ethyl 3-(1-methyl-1H-indol-3-yl)acrylate(113660-41-6)

Safety Data

• Hazardous Substances Data: 113660-41-6(Hazardous Substances Data)

Upstream product

• 81471-20-7 3-bromo-1-methyl-1H-indole 
• 140-88-5 ethyl acrylate 
• 85092-84-8 3-iodo-1-methyl-1H-indole 

Downstream Products

• 205884-12-4 (2E)-3-(1-methyl-1H-indol-3-yl)prop-2-enoic acid 

Relevant articles and documents

A Pd-mediated approach to the synthesis of an unusual β- hydroxytryptophan amino acid constituent of cyclomarin A

A synthetic approach based on a palladium-mediated vinylation of indole derivatives was established for the preparation of 5, a key intermediate in the synthesis of N-(tert-butoxycarbonyl)-L-1H-[(R)-1,1-dimethyl-2,3-epoxypropyl]- β-hydroxytryptophan ethyl ester (6). Unsatisfying yields were obtained using N-alkyl-3-haloderivatives. The best method proved to be the oxidative coupling on 3-unsubstituted indole derivative. Georg Thieme Verlag Stuttgart.