113665-89-7 Usage
Description
8,9-Z-Avermectin B1a, a member of the avermectin class of macrocyclic lactones, is a potent broad-spectrum antiparasitic agent. It is characterized by its ability to target the nervous system of parasites, causing paralysis and ultimately leading to their death. 8,9-Z-AVERMECTINB1A is known for its effectiveness, low toxicity to mammals, and its selective targeting of parasites, making it a valuable asset in the fight against a wide range of parasitic diseases.
Uses
Used in Veterinary Medicine:
8,9-Z-Avermectin B1a is used as an antiparasitic agent for the control and treatment of various parasitic infestations in livestock and domestic animals. Its broad-spectrum activity and low toxicity profile make it an ideal choice for maintaining the health of animals in various farming and breeding operations.
Used in Human Medicine Research:
8,9-Z-Avermectin B1a is being investigated for potential use in human medicine as a treatment for various parasitic infections. Its effectiveness against a wide range of parasites, coupled with its low toxicity to humans, positions it as a promising candidate for further research and development in the medical field.
Used in Parasite Control Programs:
In public health and disease control initiatives, 8,9-Z-Avermectin B1a is used as a key component in combating parasitic diseases that affect human populations. Its broad-spectrum activity and low toxicity make it suitable for large-scale distribution and administration in areas where parasitic infections are prevalent.
Used in Agricultural Applications:
8,9-Z-Avermectin B1a is also utilized in agriculture to protect crops from pests and parasites. Its ability to selectively target parasites without causing significant harm to non-target organisms makes it an environmentally friendly option for integrated pest management strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 113665-89-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,6,6 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 113665-89:
(8*1)+(7*1)+(6*3)+(5*6)+(4*6)+(3*5)+(2*8)+(1*9)=127
127 % 10 = 7
So 113665-89-7 is a valid CAS Registry Number.
InChI:InChI=1/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25?,26-,28-,30?,31?,33+,34-,35?,36?,37?,38?,39?,40+,41?,42?,43+,44?,45+,47+,48+/m0/s1
113665-89-7Relevant articles and documents
Conversion of avermectin B1 to 19-epi-avermectin B1
Blizzard,Bostrom,Margiatto,Mrozik,Fisher
, p. 2723 - 2726 (2007/10/02)
Avermectin B1 (1) has been converted to 19-epi-avermectin B1 (2) in six steps. Analog 2 retains some bioactivity but is substantially less bioactive than 1.
Studies on the deconjugation-epimerization strategy en route to avermectin B(1a): Problems and solutions
Hanessian,Dube,Hodges
, p. 7063 - 7067 (2007/10/02)
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