1136667-46-3Relevant academic research and scientific papers
Efficient one-pot synthesis of spirooxindole derivatives bearing hexahydroquinolines using multicomponent reactions catalyzed by ethylenediamine diacetate
Kang, Sorang,Lee, Yongrok
, p. 2593 - 2599 (2013/09/24)
A simple and efficient one-pot synthesis of biologically interesting spirooxindole derivatives bearing hexahydroquinoline skeleton was accomplished by EDDA-catalyzed, three-component reactions between isatins, malononitrile, and enaminones in good yields. The value of this methodology lies in its inexpensive and nontoxic organocatalyst, mild reaction conditions, and ease of handling.
Microwave-assisted synthesis of new spiro[indoline-3,4'-quinoline] derivatives via a one-pot multicomponent reaction
Zhu, Song-Lei,Zhao, Kai,Su, Xiao-Ming,Ji, Shun-Jun
experimental part, p. 1355 - 1366 (2009/10/09)
A simple and efficient synthesis of spiro[indoline-3,4'-quinoline] derivatives by a one-pot reaction of isatin, malononitrile, and enaminone under microwave irradiation was investigated. This protocol has the advantages of short reaction time, high yields
