113669-21-9 Usage
General Description
1,2-dioleoyloxy-3-(trimethylammonium)propane, also known as DOTAP, is a cationic lipid commonly used in the formulation of lipid-based nanoparticles for drug delivery and gene therapy. It consists of a glycerol backbone with two oleic acid chains and a trimethylammonium headgroup. The positively charged headgroup allows for electrostatic interactions with negatively charged molecules, such as nucleic acids, enabling efficient encapsulation and delivery of these cargo molecules into cells. DOTAP has been widely studied for its ability to deliver various therapeutic agents, including small molecule drugs, siRNA, and DNA, and has shown promise as a versatile and effective delivery vehicle for biomedical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 113669-21-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,6,6 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 113669-21:
(8*1)+(7*1)+(6*3)+(5*6)+(4*6)+(3*9)+(2*2)+(1*1)=119
119 % 10 = 9
So 113669-21-9 is a valid CAS Registry Number.
InChI:InChI=1/C42H80NO4/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,40H,6-19,24-39H2,1-5H3/q+1/b22-20-,23-21-