113676-50-9

Usage

Uses

1. Used in Pharmaceutical Industry:
DL-Glycerin-1-n-nonylether is used as an excipient for enhancing the solubility and bioavailability of poorly water-soluble drugs. Its emulsifying properties also make it suitable for formulating drug delivery systems, such as emulsions and microemulsions.
2. Used in Anticancer Applications:
DL-Glycerin-1-n-nonylether is used as a constituent of hexadecylphosphocholine (miltefosine), an anticancer agent. It plays a role in the formulation of the drug, improving its delivery and efficacy against cancer cells.
3. Used in Antifungal Applications:
DL-Glycerin-1-n-nonylether is found to be synergistic with amphotericin B against fungi. Its presence enhances the antifungal activity of amphotericin B, making it a valuable component in the development of antifungal drugs.
4. Used in Cosmetics Industry:
DL-Glycerin-1-n-nonylether is used as an emollient, emulsifier, and solubilizer in the formulation of cosmetics and personal care products. Its ability to improve the texture and stability of formulations makes it a popular ingredient in creams, lotions, and other skincare products.
5. Used in Food Industry:
DL-Glycerin-1-n-nonylether is used as an additive in the food industry, where it serves as an emulsifier, stabilizer, and wetting agent. It helps to improve the texture, consistency, and shelf life of various food products.
6. Used in Industrial Applications:
DL-Glycerin-1-n-nonylether is used as a component in the formulation of various industrial products, such as lubricants, paints, and coatings. Its emulsifying and solubilizing properties make it a valuable additive in these applications.

InChI:InChI=1/C12H26O3/c1-2-3-4-5-6-7-8-9-15-11-12(14)10-13/h12-14H,2-11H2,1H3

Upstream product

• 97030-23-4 3-non-1-en-t-yloxy-propane-1,2-diol 
• 96-24-2 3-monochloro-1,2-propanediol 
• 143-08-8 nonyl alcohol 
• 693-58-3 1-Bromononane 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 112-05-0 nonanoic acid 
• 56-81-5 glycerol 
• 1731-84-6 nonanoic acid methyl ester 
• 92039-13-9 [2-(1-bromo-octyl)-[1,3]dioxolan-4-yl]-methanol 

Relevant academic research and scientific papers

ACID LABILE SURFACTANTS

This invention relates to an acid labile surfactant. In particular, the surfactants of the present invention include a dioxolane or dioxane functional group which enables the surfactant to hydrolyze in an acidic environment. Surfactants of this type can be utilized to enhance protein solubilization/enzyme digestion. Following hydrolysis to destroy the surfactant (which may chromatographic issues), there are generally two components formed—a hydrophilic one, and a hydrophobic one. By altering the chemistry of the hydrolysable linker, the polarity of the hydrophobic residue can be altered, allowing it to be solubilized by significantly less organic solvent, and to minimize the potential loss of peptide material and to expand the chromatographic conditions that can be utilized.

PROCESS FOR PREPARING A POLYOL ETHER

The present invention relates to a process for preparing a polyol ether of formula (I), comprising a step of reductive alkylation involving a compound of general formula (II) and a compound of general formula (III): in which R1, R2, R3 and R4 are as defined in claim 1.

A comparative study of the liquid-crystalline behavior of three homologous series of 1,2-propanediol derivatives

Homologous series (R = n-hexyl to n-tetradecyl) of 3-(alkylamino)-, 3-(alkylthio)- and 3-alkoxy-1,2-propanediols have been synthesized and their thermal behavior studied by thermomicroscopy and differential-scanning calorimetry.The occurence of liquid-crystalline behavior was found to be strongly dependent on both the alkyl-chain length and the hetero-atom that links the alkyl chain to the 1,2-propanediol moiety. No thermotropic liquid-crystalline behavior could be observed for 3-alkoxy-1,2-propanediols; 3-(heptylamino)- through 3-(nonylamino)-1,2-propanediol exhibit a transient smectic A phase on supercooling of the isotropic liquid, whereas 3-(hexylthio)-1,2-propanediol through 3-(nonylthio)-1,2-propanediol form smectic phases that are quite stable.Although the thermal behavior in the pure form differs considerably, all three classes of compounds are capable of lyotropic mesophase formation in the presence of water.