1136860-35-9Relevant academic research and scientific papers
Development of dual-acting prodrugs for circumventing multidrug resistance
Abu Ajaj, Khalid,Kratz, Felix
, p. 995 - 1000 (2009)
We have developed a novel dual-acting maleimide-bearing prodrug that incorporates the anticancer agent doxorubicin and an inhibitor of the P-glycoprotein efflux pump that is over-expressed in multidrug resistant tumor cells. Additionally, the prodrug cont
