1137-65-1Relevant academic research and scientific papers
Convenient Structural Diversity-Guided Synthesis of Functionalized Sulfur-Containing Heterocycles via α-Substituted Cyanoacetamides
Ke, Shaoyong
, p. 1957 - 1962 (2017/05/29)
A convenient molecular diversity-oriented synthesis of various functional sulfur-containing heterocyclic scaffolds mainly including isothiazole, 2H-1,3-thiazine, and thiazolidine via different methods from α-substituted cyanoacetamides is described. The target molecules have been identified on the basis of analytical spectral data, which may serve as useful structural subunits in the fields of drug discovery.
A Facile Synthesis of 3-Amino-5-substitutedaminoisothiazole-4-carboxylic Acid Derivatives
Shishoo, C. J.,Devani, M. B.,Ananthan, S.,Bhadti, V. S.,Ullas, G. V.
, p. 759 - 765 (2007/10/02)
A facile, general and one-pot method for the preparation of 3-amino-5-substituted-aminoisothiazole-4-carboxylic acid derivatives, in high yields, by the aminative cyclization of 3-amino-3-mercaptoacrylonitriles is described.
