1137279-00-5

Basic information

• Product Name: 4-(5-chloro-2-(methylthio)thiazolo[4,5-d]pyrimidin-7-yl)morpholine
• Synonyms: 4-(5-chloro-2-(methylthio)thiazolo[4,5-d]pyrimidin-7-yl)morpholine;5-Chloro-2-(methylthio)-7-(morpholin-4-yl)thiazolo[4,5-d]pyrimidine;Thiazolo[4,5-d]pyriMidine, 5-chloro-2-(Methylthio)-7-(Morpholin-4-yl)-;5-chloro-2-(methylthio)-7-(4-morpholinyl)Thiazolo[4,5-d]pyrimidine
• CAS NO: 1137279-00-5
• Molecular Formula: C10H11ClN4OS2
• Molecular Weight: 302.80354
• Mol File: 1137279-00-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 424.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.56
• PKA: 1.28±0.50(Predicted)
• CAS DataBase Reference: 4-(5-chloro-2-(methylthio)thiazolo[4,5-d]pyrimidin-7-yl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-chloro-2-(methylthio)thiazolo[4,5-d]pyrimidin-7-yl)morpholine(1137279-00-5)
• EPA Substance Registry System: 4-(5-chloro-2-(methylthio)thiazolo[4,5-d]pyrimidin-7-yl)morpholine(1137279-00-5)

Safety Data

• Hazardous Substances Data: 1137279-00-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 87789-35-3 5,7-dichloro-2-(methylthio)thiazolo[4,5-d]pyrimidine 

Downstream Products

• 1137278-92-2 5-chloro-2-(methylsulfonyl)-7-morpholinothiazolo[4,5-d]pyrimidine 

Relevant articles and documents

THIAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Compounds of Formulas (Ia and Ib), and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed