1137359-47-7 Usage
Description
BRD7552 is a small molecule that induces expression of pancreatic and duodenal homeobox 1 (PDX1), a transcription factor involved in pancreas development and function. BRD7552 dose-dependently increases PDX1 and insulin gene expression, as well as PDX1 protein levels, in PANC-1 cells. It also increases acetylation of histone H3 and trimethylation of H3K4 and H3K9.
Uses
BRD7552 upregulates PDX1 expression in both primary human islets and ductal cells.
Check Digit Verification of cas no
The CAS Registry Mumber 1137359-47-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,7,3,5 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1137359-47:
(9*1)+(8*1)+(7*3)+(6*7)+(5*3)+(4*5)+(3*9)+(2*4)+(1*7)=157
157 % 10 = 7
So 1137359-47-7 is a valid CAS Registry Number.