1137439-79-2Relevant academic research and scientific papers
Rapid access to benzo-annelated heterocycles, naphthalenes, and polysubstituted benzenes through a novel benzannulation reaction
Cikotiene, Inga,Buksnaitiene, Rita,Sazinas, Rokas
experimental part, p. 706 - 717 (2011/03/19)
A novel, efficient, and powerful methyl mercaptoacetate triggered benzannulation reaction is described. The precursors are heterocyclic, aromatic or acyclic compounds bearing a carbonyl group at ortho position to an internal alkyne. The methodology does not require transition-metal catalysts and moreover it is general for the preparation of wide range of benzo-annelated heterocycles, naphthalenes and benzenes.
The first and efficient synthesis of 7-aryl-6-methoxycarbonylquinazolines via unexpected reaction of 6-arylethynylpyrimidine-5-carbaldehydes and methyl mercaptoacetate
Cikotiene, Inga,Morkunas, Marius
body text, p. 284 - 286 (2009/06/23)
A highly concise synthesis of 7-aryl-6-methoxycarbonylquinazolines via reaction of 6-arylethynylpyrimidine-5-carbaldehydes and methyl mercaptoacetate is described. Georg Thieme Verlag Stuttgart.
