113767-80-9Relevant academic research and scientific papers
Method for synthesizing alkyne through catalytic asymmetric cross coupling (by machine translation)
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Paragraph 0408; 0410, (2020/01/12)
The invention belongs to the field of, asymmetric synthesis, and discloses a method for catalyzing asymmetric cross- coupling to synthesize: an alkyne, and the L method comprises, the following steps, of A: preparing B a cuprous, salt and C a: ligand; preparing a catalyst; adding a base; reacting the compound with the compound with the compound; and reacting the compound with the compound. Of these, one of them, X is selected from the group consisting of, R halogens. 1 Optionally substituted heteroarylsulfonylcyanamide groups selected from the, group consisting, of optionally substituted, phenyl groups In-flight vehicle, R6 Trialkyl silyl groups or alkyl radicals, R2 Cycloalkyl radicals optionally substituted with an, optionally substituted alkyl, (CH radical2 )n R4 Multi,layer chain, n＝0-10,R saw blade4 A group selected, from, the group consisting of phenyl, alkenyl, aralkynyls, noonyloxy,and, noonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylphenyl disiloxy-radicals. R3 A ligand, selected from hydrogen or any of the functional groups, is selected from the group consisting of, hydrogen and any L other functional group. The method, R disclosed by the, A invention has the, advantages of good catalytic, R ’ effect, wide application range. and high catalytic efficiency, and the, method disclosed by the, invention has the. advantages of good catalytic effect, wide application range and high catalytic efficiency. (by machine translation)
Antiviral activity of diarylheptanoid stereoisomers against respiratory syncytial virus in vitro and in vivo
Konno, Katsuhiko,Miura, Motofumi,Toriyama, Masaharu,Motohashi, Shigeyasu,Sawamura, Rie,Watanabe, Wataru,Yoshida, Hiroki,Kato, Masahiko,Yamamoto, Ryuichi,Yasukawa, Ken,Kurokawa, Masahiko
, p. 773 - 781 (2013/09/24)
We previously showed that (5S)-5-hydroxy-7-(4-hydroxyphenyl)-1-phenylhept- 3-one (AO-0011) and (5S)-5-methoxy-1,7-diphenylhept-3-one (AO-0016) isolated from Alpinia officinarum exhibited stronger anti-influenza virus activity and anti-respiratory syncytia
Regio- and Stereoselective Synthesis of Allylic and Homoallylic Alcohols by the Reductive Desulfonylation of Allylic Sulfone Derivatives. Application to the Syntheses of (+/-)-Lavandulol and Isolavandulol
Inomata, Katsuhiko,Igarashi, Susumu,Mohri, Mitsunobu,Yamamoto, Taku,Kinoshita, Hideki,Kotake, Hiroshi
, p. 707 - 710 (2007/10/02)
Regio- and stereoselective desulfonylation of β-tosylhomoallylic alcohols provided a convenient method for the preparation of allylic and homoallylic alcohols. (+/-)-Lavandulol and isolavandulol were synthesized in excellent yields by this method.
