1137726-40-9

Basic information

• Product Name: 5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole
• Synonyms: 5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole
• CAS NO: 1137726-40-9
• Molecular Weight: 451.546
• Mol File: 1137726-40-9.mol

Chemical Properties

• CAS DataBase Reference: 5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole(1137726-40-9)
• EPA Substance Registry System: 5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole(1137726-40-9)

Safety Data

• Hazardous Substances Data: 1137726-40-9(Hazardous Substances Data)

Upstream product

• 1137726-30-7 diethyl 2-((2-(bromomethyl)-5-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl)methylene)malonate 
• 90-12-0 1-Methylnaphthalene 
• 1332607-79-0 [5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate 
• 1273320-50-5 C₂₁H₂₀BrNO₇S 
• 164261-31-8 5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indole-3-carbaldehyde 

Relevant articles and documents

Lewis acid mediated one-pot synthesis of aryl/heteroaryl-fused carbazoles involving a cascade Friedel-Crafts alkylation/electrocyclization/aromatization reaction sequence

A Lewis-acid-mediated domino reaction of 2/3-(bromomethyl)indoles with arenes/heteroarenes led to the formation of the corresponding annulated carbazoles. This three-step one-pot transformation proceeds by sequential Lewis acid catalysed Friedel-Crafts alkylation, electrocyclization and aromatization reactions. The strategy is highly efficient for the assembly of complex aryl/heteroaryl-fused carbazoles.

A versatile synthesis of annulated carbazole analogs involving a domino reaction of bromomethylindoles with arenes/heteroarenes

A ZnBr2-mediated arylation of aryl/heteroaryl methyl bromides with arenes at 80°C led to the formation of arylated products, which underwent subsequent 1,5-sigmatropic rearrangement followed by electrocyclization and aromatiza tion with loss of a diethylmalonate unit to afford the corresponding annulated products.