113778-75-9

Usage

Functional groups

Ketone, Benzyl ether, Methyl group

Structure

A ketone derivative with a benzyl ether group attached to the oxygen atom and a methyl group attached to the second carbon of the parent chain

Usage

Commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and natural products

Stability

Aromatic benzyl group provides stability and makes it suitable for a wide range of reactions

Applications

Studied for potential applications in medicinal chemistry and drug development due to its unique structure and reactivity

Upstream product

• 80325-76-4 1-(benzyloxy)-3-methylbutan-2-ol 
• 60656-87-3 benzyloxyacetoaldehyde 
• 31600-43-8 methyl 2-(benzyloxy)acetate 

Downstream Products

• 113778-70-4 (4R^*,5R^*)-2,6-dimethyl-5-hydroxy-4-(phenylmethoxy)-3-heptanone 
• 113778-71-5 (4R^*,5S^*)-2,6-dimethyl-5-hydroxy-4-(phenylmethoxy)-3-heptanone 
• 113778-73-7 (3R,5R)-4-Benzyloxy-2,6-dimethyl-heptane-3,5-diol 
• 113830-24-3 (3R,4R,5S)-4-Benzyloxy-2,6-dimethyl-heptane-3,5-diol 
• 113830-23-2 (3S,4S,5R)-4-Benzyloxy-2,6-dimethyl-heptane-3,5-diol 
• 113778-74-8 syn-anti-2,6-dimethyl-4-(phenylmethoxy)-3,5-heptanediol acetonide 
• 113778-74-8 (4S,5R,6R)-5-Benzyloxy-4,6-diisopropyl-2,2-dimethyl-[1,3]dioxane 
• 113778-72-6 anti-anti-2,6-dimethyl-4-(phenylmethoxy)-3,5-heptanediol acetonide 
• 1383003-21-1 2-(benzyloxy)methyl-2-isopropyl-1,3-dioxolane 

Relevant academic research and scientific papers

Copper(I)-catalyzed asymmetric desymmetrization: Synthesis of five-membered-ring compounds containing all-carbon quaternary stereocenters

A highly stereoselective catalytic alkylation sequence for the synthesis of highly functionalized and versatile five-membered-ring compounds bearing all-carbon quaternary stereocenters was developed. Enantioselective desymmetrization of achiral cyclopentene-1,3-diones was thus executed by chiral Cu-phosphoramidite catalysts. A variety of complicated cyclopentane derivatives can be synthesized with excellent stereoselectivities using a low catalyst loading in a one-pot operation.

Convenient preparation of carbonyl compounds from 1,2-diols utilizing Mitsunobu conditions

1,1-Disubstituted 1,2-diols are efficiently converted into carbonyl compounds by reaction with triphenylphosphine and diethyl azodicarboxylate. (C) 2000 Elsevier Science Ltd.