1137949-68-8

Basic information

• Product Name: 3-Bromopyrazolo[1,5-b]pyridazine
• Synonyms: 3-Bromopyrazolo[1,5-b]pyridazine
• CAS NO: 1137949-68-8
• Molecular Formula: C₆H₄BrN₃
• Molecular Weight: 198.02006
• Mol File: 1137949-68-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.891 g/cm³
• PKA: 0.46±0.30(Predicted)
• CAS DataBase Reference: 3-Bromopyrazolo[1,5-b]pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromopyrazolo[1,5-b]pyridazine(1137949-68-8)
• EPA Substance Registry System: 3-Bromopyrazolo[1,5-b]pyridazine(1137949-68-8)

Safety Data

• Hazardous Substances Data: 1137949-68-8(Hazardous Substances Data)

Usage

General Description

3-Bromopyrazolo[1,5-b]pyridazine is a chemical compound with the molecular formula C6H3BrN4. It is a heterocyclic organic compound that consists of a pyridazine ring fused with a pyrazole ring. 3-Bromopyrazolo[1,5-b]pyridazine is used in scientific research and drug development, particularly in the synthesis and study of other heterocyclic compounds. It is also utilized as a building block in the creation of various pharmaceuticals and agrochemicals. 3-Bromopyrazolo[1,5-b]pyridazine has properties that make it valuable in the development of organic materials and can contribute to advancements in the fields of medicine and agriculture.

Upstream product

• 53946-83-1 methyl pyrazolo[1,5-b]pyridazine-3-carboxylate 
• 88561-91-5 pyrazolo[1,5-b]pyridazine-3-carboxylic acid 

Downstream Products

• 1146395-28-9 (4-pyrazolo[1,5-b]pyridazin-3-ylphenyl)acetic acid 
• 1202177-91-0 (E)-(3,4-difluorophenyl){5-[(7-pyrazolo[1,5-b]pyridazin-3-yl-2,7-diazaspiro[4.4]non-2-yl)methyl]-2-pyridinyl}methanone O-ethyloxime 

Relevant articles and documents

Decarboxylative Bromination of Heteroarenes: Initial Mechanistic Insights

After an initial report from our laboratory describing metal-free decarboxylative halogenation of various azaheteroarenes, we set out to investigate the possible mechanism by which this chemistry occurs. Evidence from this mechanistic investigation sugges

Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5- b]pyridazines for the Treatment of Human African Trypanosomiasis

From a high-throughput screen of 42 44 known human kinases inhibitors, a pyrazolo[1,5-b]pyridazine scaffold was identified to begin optimization for the treatment of human African trypanosomiasis. Previously reported data for analogous compounds against h