1138018-24-2

Basic information

• Product Name: 1-Benzyl 5-Methyl N,N-bis(tert-butoxycarbonyl)-L-glutaMate
• Synonyms: 1-Benzyl 5-Methyl N,N-bis(tert-butoxycarbonyl)-L-glutaMate
• CAS NO: 1138018-24-2
• Molecular Formula: C₂₃H₃₃NO₈
• Molecular Weight: 451.51002
• Mol File: 1138018-24-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzyl 5-Methyl N,N-bis(tert-butoxycarbonyl)-L-glutaMate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl 5-Methyl N,N-bis(tert-butoxycarbonyl)-L-glutaMate(1138018-24-2)
• EPA Substance Registry System: 1-Benzyl 5-Methyl N,N-bis(tert-butoxycarbonyl)-L-glutaMate(1138018-24-2)

Safety Data

• Hazardous Substances Data: 1138018-24-2(Hazardous Substances Data)

Usage

Uses

1-Benzyl 5-methyl N,N-bis(tert-butoxycarbonyl)-L-glutamate is used in the synthesis of Isodesmosine Chloride (I815050), which is a component of elastin.

Upstream product

• 30924-93-7 Boc-Glu-OBn 
• 132245-78-4 (S)-2-tert-butoxycarbonylaminopentanedioic acid 1-benzyl ester 5-methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1138018-25-3 2-(S)-[bis(tert-butoxycarbonyl)amino]-5-oxo-pentanoic acid benzyl ester 
• 1370623-34-9 (S,E)-7-benzyl 1-(tert-butyl) 6-(bis((tert-butoxy)carbonylamino))hept-2-enedioate 

Relevant articles and documents

Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction

We have developed a novel bioorthogonal reaction that can selectively displace fluorine substitutions alpha to amide bonds. This fluorine-thiol displacement reaction (FTDR) allows for fluorinated cofactors or precursors to be utilized as chemical reporters, hijacking acetyltransferase-mediated acetylation both in vitro and in live cells, which cannot be achieved with azide- or alkyne-based chemical reporters. The fluoroacetamide labels can be further converted to biotin or fluorophore tags using FTDR, enabling the general detection and imaging of acetyl substrates. This strategy may lead to a steric-free labeling platform for substrate proteins, expanding our chemical toolbox for functional annotation of post-translational modifications in a systematic manner.

METHOD FOR PRODUCING DESMOSINE, ISODESMOSINE AND DERIVATIVES THEREOF

A process for preparing a compound represented by the following general formula (I) or a salt thereof, which comprises reacting lysine or a protective product thereof or a salt thereof with allysine or a protective product thereof in the presence of a spe

Efficient synthesis of benzyl 2-(S)-[(tert-butoxycarbonyl)amino]-ω- iodoalkanoates

The efficient synthesis of four benzyl 2-(S)-[(tert-butoxycarbonyl)amino]- ω-iodoalkanoates {benzyl 2-(S)-[(tert-butoxycarbonyl)amino]-3- iodopropanoate, benzyl 2-(S)-[(tert-butoxycarbonyl)amino]-4-iodobutanoate, benzyl 2-(S)-[(tert-butoxycarbonyl)amino]-