1138239-07-2Relevant academic research and scientific papers
Stereoselective total synthesis of goniothalesdiol A via chiron approach
Yadav, Jhillu S.,Nageshwar Rao, Ragam,Somaiah, Ragam,Harikrishna, Valaboju,Subba Reddy, Basi V.
experimental part, p. 1362 - 1368 (2010/09/20)
The stereocontrolled synthesis of goniothalesdiol A, a dihydroxylated tetrahydropyran compound, has been accomplished using d-ribose as chiral precursor. The key steps involved are aryl Grignard reaction, stereoselective alkoxy-directed keto reduction, and intramolecular oxy-Michael addition.
First stereoselective total synthesis of Goniothalesdiol A
Yadav,Rami Reddy,Harikrishna,Subba Reddy
scheme or table, p. 1318 - 1320 (2009/06/28)
The first total synthesis of Goniothalesdiol A, isolated from the stems of Goniothalamus amuyon (Annonaceae) is reported. The C2 stereocentre and C3/C4 syn diol were created by a Sharpless kinetic resolution followed by acetonide formation. The tetrahydro
