1138245-13-2

Usage

Uses

Used in Pharmaceutical Industry:
2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid is used as a pharmaceutical compound for the development of new drugs. Its unique structure and functional groups may allow it to interact with specific biological targets, potentially leading to the creation of novel therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid can be used as a starting material or intermediate in the synthesis of more complex molecules. Its specific stereochemistry and functional groups make it a valuable tool for studying reaction mechanisms and developing new synthetic methods.
Used in Material Science:
The unique structure of 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid may also find applications in material science, where it could be used to develop new materials with specific properties. Its potential use in this field would depend on further research and development to understand its properties and how it can be integrated into various materials.

Upstream product

• 1138246-20-4 tert-butyl [(1R,5S,6S)-6-(tert-butoxycarbonylamino)methyl-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetate 
• 1235479-61-4 (1R,5S)-3-ethylbicyclo[3.2.0]hept-3-en-6-one 

Downstream Products

• 1138245-21-2 [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate 

Relevant academic research and scientific papers

Novel method for preparing Mirogabalin

The invention relates to a novel method for preparing racemic Mirogabalin. The preparation method comprises the following steps: with 3-ethylbicyclo[3.2. 0]hepta-3-ene-6-ketone A as an initial raw material, carrying out a reaction with cyanoacetate and ammonia water to generate ammonium salt B; heating the ammonium salt B and sulfuric acid to react to generate a diacetic acid compound C; carryingout a reaction on the compound C with urea to generate an imide compound D; degrading the compound D through Hofmann to generate racemic Mirogasabalin hydrochloride E, and then enabling the compound Eto pass through a resolving agent to obtain the Mirogasabalin. Compared with the prior art, the Mirogabalin drug synthesized by the technical scheme of the invention has the characteristics that thereaction condition is mild, the preparation method is simple and convenient, the use of a highly toxic product NaCN is avoided, and the Mirogabalin drug is suitable for industrial production.

METHOD FOR PRODUCING OPTICALLY ACTIVE BICYCLIC -AMINO ACID DERIVATIVE

An object of the present invention is to provide an optically active bicyclic γ-amino acid derivative in a high purity. The object can be attained by a mixture of compounds represented by the general formulas (I) and (I'), or a method for producing a compound represented by the general formula (VII) or a salt thereof via the compound (I): wherein R1 and R2 each represent a C1-6 alkyl group or the like; and R3 represents a cyano group or the like,

BICYCLIC -AMINO ACID DERIVATIVE

It is intended to provide a bicyclic γ-amino acid derivative having excellent activity as an α2δ ligand. The present invention provides a compound represented by the general formula (I): wherein R1, R2, R2', R4, R5, R6, R7, R8, and R8' are a hydrogen atom or the like; and R3 is a hydrogen atom, a halogen atom, a C1-C6 alkyl group, or the like.