1138320-71-4

Basic information

• Product Name: 3-[(4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione
• CAS NO: 1138320-71-4
• Molecular Weight: 235.266
• Mol File: 1138320-71-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[(4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione(1138320-71-4)
• EPA Substance Registry System: 3-[(4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione(1138320-71-4)

Safety Data

• Hazardous Substances Data: 1138320-71-4(Hazardous Substances Data)

Upstream product

• 5339-74-2 4-hydroxybenzaldehyde thiosemicarbazone 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 5466-23-9 bis(4-hydroxybenzylidene)hydrazine 
• 1138320-74-7 3-[(3-phenylazo-4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione 
• 1138320-75-8 1-acetyl-3-[(4-acetoxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione 
• 1138320-72-5 1-benzyl-3-[(4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione 
• 1138320-76-9 5-(4-hydroxy)benzylidene-3-[(4-hydroxybenzylidene)-amino]-4-oxo-imidazolidin-2-thione 
• 1138320-73-6 methyl β-[3-[(4-hydroxybenzylidene)-amino]-4-oxo-2-thioxo-imidazolidin-1-yl]propionate 

Relevant articles and documents

Use of ethyl β-(4-hydroxyphinyl)-α-cyanoacrylate in the synthesis of carbazone, thiazole and imidazolidin-2-thione derivatives

CONDENSATION of ethyl β-(4-hydroxyphenyl)-α-cyanoacrylate with thiosemicarbazide gave the 4-hydroxybenzaldehyde thiosemicarbazone (3). Treatment of 3 with acetic anhydride, 4-substituted phenacyl bromide and ethyl chloroacetate yielded the corresponding N-acetyl derivative (4), thiazol derivative (5) and 3-substituted 4-oxo-imidazolidin-2-thione (6). Compound 6 reacted with benzyl chloride, methyl acrylate, phenyl- diazonium chloride and hydrazine hydrate to give 1-substituted imidazo-lidine-2-thione derivatives (7,8,9) and 1,2-bis (4-hydroxy-benzal-dehyde)-hydrazone (10). Treatment of 6 with acetic anhydride and 4-hydroxybenzaldehyde afforded the corresponding N-acetyl derivatives (11) and 5-substitued-imidazolidin-2-thione (12). The mass spectral fragmentation patterns of some compounds are described.