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2,5-Cyclohexadiene-1,4-dione, 2,3-dimethyl-5,6-bis(methylthio)-, also known as Thioflavin T, is a chemical compound that serves as a fluorescent dye for the detection and quantification of amyloid fibrils, which are protein aggregates implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's. Thioflavin T exhibits a yellow-green fluorescent emission when bound to these fibrils, making it a valuable tool in the study and diagnosis of amyloid-related pathologies.

113845-74-2

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113845-74-2 Usage

Uses

Used in Neurodegenerative Disease Research:
Thioflavin T is used as a fluorescent dye for the detection and quantification of amyloid fibrils in neurodegenerative disease research. Its fluorescent properties allow for the visualization and analysis of these protein aggregates, which are associated with diseases like Alzheimer's and Parkinson's.
Used in Therapeutic Agent Development:
Thioflavin T is being studied for its potential as a therapeutic agent for amyloid-related diseases. Its ability to inhibit amyloid fibril formation and promote the clearance of existing fibrils makes it a promising candidate for the development of treatments aimed at reducing the impact of these protein aggregates on neuronal function and health.

Check Digit Verification of cas no

The CAS Registry Mumber 113845-74-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,8,4 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 113845-74:
(8*1)+(7*1)+(6*3)+(5*8)+(4*4)+(3*5)+(2*7)+(1*4)=122
122 % 10 = 2
So 113845-74-2 is a valid CAS Registry Number.

113845-74-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-dimethyl-5,6-bis(methylsulfanyl)cyclohexa-2,5-diene-1,4-dione

1.2 Other means of identification

Product number -
Other names 2,3-dimethylthioxyloquinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:113845-74-2 SDS

113845-74-2Relevant academic research and scientific papers

SOME SULFUR AND NITROGEN SUBSTITUTED XYLOQUINONES

Wladislaw, B.,Marzorati, L.,Netto, S. Lima

, p. 173 - 178 (2007/10/02)

This paper reports reactions of dihalogeno-xyloquinone with sulfur and nitrogen nucleophiles, leading to the di- and mono-substituted derivatives, respectively.The mixed nitrogen-sulfur and carbon-nitrogen derivatives were also synthesized.New reactions,

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