113863-08-4

Basic information

• Product Name: 2,3-bis(4-ethoxyphenyl)-1H-inden-1-one
• Synonyms: 2,3-bis(4-ethoxyphenyl)-1H-inden-1-one
• CAS NO: 113863-08-4
• Molecular Weight: 370.448
• Mol File: 113863-08-4.mol

Chemical Properties

• CAS DataBase Reference: 2,3-bis(4-ethoxyphenyl)-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-bis(4-ethoxyphenyl)-1H-inden-1-one(113863-08-4)
• EPA Substance Registry System: 2,3-bis(4-ethoxyphenyl)-1H-inden-1-one(113863-08-4)

Safety Data

• Hazardous Substances Data: 113863-08-4(Hazardous Substances Data)

Upstream product

• 101451-64-3 ((Ξ)-4-ethoxy-benzylidene)-phthalide 
• 41842-30-2 4-ethoxyphenylmagnesium bromide 
• 2132-63-0 1,2-bis(4-ethoxyphenyl)ethyne 
• 611-73-4 Benzoylformic acid 
• 611-71-2 MANDELIC ACID 

Relevant articles and documents

Rhodium-Catalyzed Oxidative Decarboxylation Annulation Reactions of Mandelic Acids and Alkynes: An Efficient Synthetic Method for Indenones

Efficient rhodium-catalyzed oxidative decarboxylation annulation reactions between mandelic acids and alkyne derivatives are described. The desired indenone products were obtained in medium to good yields under the optimized reaction conditions, which were a [RhCp*Cl2]2 catalyst (10.0 mol %) in combination with a PCy3 ligand (10.0 mol %) and AgSbF6 (10 mol %) and Cu(OAc)2 (20 mol %) additives. Many functional groups are compatible with the reaction under the optimized reaction conditions. This strategy provides a promising method for the construction of indenones from cheap and commercially available starting materials.

Efficient indenones synthesis via iridium-catalyzed decarboxylative annulation between 2-oxo-2-phenylacetic acids and alkynes

Efficient iridium-catalyzed decarboxylative annulation reactions between 2-oxo-2-phenylacetic acids and alkyne derivatives has been achieved. [IrCp*Cl2]2 with a (CH3OC6H4)3P ligand, AgSbF6 and Cu(OAc)2 additives was the most efficient catalytic system for this transformation. This reaction is suitable for a broad range of alkynes and 2-oxo-2-phenylacetic acids and a variety of indenone derivatives were obtained in medium to high yields. This work provides an efficient approach for the construction of indenones by iridium–catalyzed decarboxylative annulation.

Synthesis method for 2,3-diphenyl-1H-indene-1-one derivatives

The invention discloses a synthesis method for 2,3-diphenyl-1H-indene-1-one derivatives. The synthesis method comprises the steps of: adding benzoyl formic acid, a diphenyl acetylene compound, pentamethyl cyclopentadiene dichloride iridium, copper acetate, silver hexafluoroantimonate and a silver hexafluoroantimonate into an organic solvent; heating for reaction in the presence of air; and after the reaction, carrying out post-treatment to obtain the 2,3-diphenyl-1H-indene-1-one derivative. The method synthesizes the 2,3-diphenyl-1H-indene-1-one derivative in one step through simple and easilyavailable raw materials, so that the conversion efficiency is high and the atomic economical benefit is good. Meanwhile, the synthetic method is simple to operate, high in reaction yield and wide inprimer adaptability.