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• 56613-80-0 D-2-phenylglycinol 
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• 89-95-2 2-methyl-benzyl alcohol 

Relevant academic research and scientific papers

Trinuclear Complexes Derived from R/S Schiff Bases – Chiral Single-Molecule Magnets

The employment of enantiomerically pure Schiff bases in manganese chemistry is revealed to be an excellent method to obtain chiral single-molecule magnets and has allowed the characterization of several pairs of enantiomers, for which the magnetic properties were investigated. The reported systems consist of MnIII–MnII–MnIIIlinear trimers or MnIII3cations in a triangular arrangement including the first example of a μ3-Cl bridge in an isolated manganese triangle.

New chiral 1,4,2-oxazaphosphorinanes bearing a free hydroxy group

New chiral 3-aryl-2-hydroxy-2-oxo-5-R-1,4,2-oxazaphosphorinanes were obtained by a three-step one-pot synthesis, which included the preparation of imines from enantiopure (2R)-2-aminoalkan-1-ols, their phosphonylation and subsequent dealkylation of the P(

Design and synthesis of enantiomeric (R)- and (S)-copper(II) and diorganotin(IV)-based antitumor agents: Their in vitro DNA binding profile, cleavage efficiency and cytotoxicity studies

New chiral reduced Schiff base ligands (R)/(S)-2-(2-hydroxy-1- phenylethylaminomethyl)phenol (L), (R)/(S)-2-(benzylamino)-2-phenylethanol (L′) and their Cu(II)/organotin(IV) complexes (1-4) were synthesized and thoroughly characterized. Preliminary in vit

Synthesis, characterization, and structures of oxovanadium(v) complexes of Schiff bases of β-amino alcohols as tunable catalysts for the asymmetric oxidation of organic sulfides and asymmetric alkynylation of aldehydes

Oxovanadium(v) complexes 3a-3k and 4a-4d with general formula VO(L 3*)(OR5) were prepared in quantitative yields in alcohol (R5OH) from reactions of VO(O-i-Pr)3 and tridentate Schiff bases of β-amino alcohols having one or two stereogenic centers, (HO)C*(R1)(R2)C*H(R 3)NCH(2-OH-3,5-R42-C6H2) (H2L3*). The alkoxy OR5 ligand exchanges readily with the alcoholic molecule in the solvent. Crystal structures of 3b, 3f, 3i, and 4a were determined to be five-coordinate square pyramidal monomers. However, 1H NMR spectra of the complexes reveal two sets of signals, indicating the presence of two isomers in solution. The two isomers are suggested to be the endo/exo pair or the monomer/dimer pair. Asymmetric oxidations of methyl phenyl sulfide catalyzed by catalyst precursors 3 were demonstrated to afford the chiral sulfoxide in yields and ee values similar to those obtained from the in situ-formed catalytic systems of VO(acac)2 and corresponding Schiff base ligands. Complexes 3 and 4 are also good catalysts for asymmetric alkynyl additions to aldehydes. Structural differences between the oxovanadium complexes, for inducing high stereoselectivities in the asymmetric oxidation of organic sulfides and the asymmetric alkynyl addition to aldehydes, are rationalized. This journal is The Royal Society of Chemistry.

A family of enantiopure FeIII4 single molecule magnets: Fine tuning of energy barrier by remote substituent

A new family of enantiopure star-shaped FeIII4 single-molecule magnets (SMMs) with the general formula [Fe4(L K)6] (H2L = (R or S)-2-((2-hydroxy-1- phenylethylimino methyl)phenol); K = H (1), Cl (2), Br (3), I (4), and t-Bu (5)), were structurally and magnetically characterized. Complex 1 was reported in our previous paper (Chem. Commun., 2011, 47, 8049-8051). Detailed magnetic measurements and a systematic magneto-structural correlation study revealed that the SMM properties of this series of compounds can be finely tuned by the remote substituent of the ligands. Although the change in the coordination environment of the central Fe3+ ions is very small, the properties of SMM behavior are changed considerably. All five complexes display frequency dependence of the ac susceptibility. However, the χ′′ac peaks of complexes 2 and 5 cannot be observed down to 0.5 K. The fitted anisotropy energy barriers (Ueff) of complexes 1, 3, and 4 were 5.9, 7.1, and 11.0 K, respectively. Moreover, the hysteresis loops of these three complexes can be also observed around 0.5 K. Magneto-structural correlation analyses revealed that the coordination symmetry of the central Fe3+ ion and the intermolecular interaction are two key factors affecting the SMM properties. Deviation to a trigonal prism coordination environment and the existence of intermolecular interactions between neighboring clusters may both reduce the anisotropy energy barriers. This journal is the Partner Organisations 2014.

Syntheses, spectroscopy, and catalysis of (η4-cod)Rh(I)- complexes with (R or S)-2-(salicylaldimine)-2-phenylethanol or (rac)-2-(salicylaldimine)-1-phenylethanol

Condensation of salicyldehyde with (R or S)-2-amino-2-phenylethanol or rac-2-amino-1-phenylethanol gives enantiopure (R or S)-2-(salicylaldimine)-2- phenylethanol (R- or S-H2L1) or (rac)-2-(salicylaldimine)-1- phenylethanol (rac-H2L2

Synthesis, characterization and X-ray studies of new six-seven membered rings [4.5.0] heterobicyclic system of monomeric boronates

Different tridentate ligands derived from ethanolamines and 2-hydroxyacetophenone, 2-hydroxybenzophenone and salicylaldehyde were reacted with two equivalents of phenylboronic acid to obtain compounds 6a-6f which are [4.5.0] heterobicyclic systems with a

New chiral molybdenum complex catalyzed sulfide oxidation with hydrogen peroxide

Six new cis-dioxomolybdenum(VI) complexes of chiral Schiff-base ligands, derived from condensation of various amino alcohols and substituted salicylaldehydes, have been prepared and characterized by NMR, IR, ESI-MS and single crystal X-ray diffraction techniques. The geometry around the molybdenum center is distorted octahedral in which a tridentate Schiff-base ligand with two anionic oxygens and one neutral imine nitrogen occupies meridional position. The octahedral geometry of the cis-dioxomolybdenum center is additionally completed by a coordinated labile solvent molecule. In some complexes the sixth site is found to be vacant where the relatively bulky substituents hinder the coordination of the solvent. These complexes are tested for catalytic enantioselective sulfoxidation reactions using hydrogen peroxide as oxidant at low temperature which shows high selectivity along with good to moderate enantiomeric excess. ESI-MS study of the reaction mixture indicates the formation of oxoperoxoMo(VI) complexes during catalysis. The steric effect originated from the substituent on chiral ligand on the catalytic reaction is also discussed. It is found that the substituents at the β position of the amino alcohol seem to greatly influence the enantioselectivity of the oxidation reactions.

Enantioselective nitroaldol (Henry) reaction catalyzed by chiral Schiff-base ligands

Chiral Schiff-bases 2, 3, 4 and 5 were designed for the enantioselective nitroaldol (Henry) reaction. The highest enantioselectivity was observed for ligand 4 (82% ee) when CH2Cl2 was used as a solvent.

Synthesis of new tridentate chiral aminoalcohols by a multicomponent reaction and their evaluation as ligands for catalytic asymmetric Strecker reaction

A one-step, multicomponent Mannich-type reaction between phenols, paraformaldehyde, and β-aminoalcohols in the presence of LiCl afforded N-2-hydroxybenzyloxazolidines with high ortho-selectivity. Hydrolytic or reductive ring opening of the oxazolidines pr