113875-20-0

Upstream product

• 88-15-3 2-Acetylthiophene 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 1349847-75-1 bis(2-acetylthiophene benzoylhydrazonato)copper(II) 
• 1349847-71-7 bis(2-acetylthiophene benzoylhydrazonato)cobalt(II) 
• 1349847-76-2 bis(2-acetylthiophene benzoylhydrazonato)zinc(II) 
• 1349847-73-9 diaquabis(2-acetylthiophene benzoylhydrazonato)nickel(II) 
• 915962-38-8 [RuCl₂(triphenylarsine)2(C₄H₃SC(Me)NNCOC₆H₅)] 
• 915962-32-2 [RuCl₂(triphenylphosphine)2(C₄H₃SC(Me)NNCOC₆H₅)] 
• 180971-34-0 Cu(C₁₃H₁₁N₂OS)2 
• 1360762-96-4 Ni(II)Br₂(N'-(1-(thiophen-2-yl)ethylene)benzohydrazide)2 
• 1361111-03-6 [Ni(II)(N'-(1-(thiophen-2-yl)ethylene)benzohydrazide(-H))2] 

Relevant academic research and scientific papers

Synthesis, spectral characterization and antibacterial activity of functionalized hydrazones

New hydrazones have been synthesized by condensing 2-acetylthiophene with acetic hydrazide and benzhydrazide. The synthesized hydrazones viz. 2-acetylthiophene acetoylhydrazone (ATAH), 2-acetylthiophene benzoylhydrazone (ATBH) are characterized in the lig

Synthesis, spectral characterization and antibacterial activity of copper(II) complexes of functionalized hydrazones

Copper(II) complexes having the formula CuL2 {where, L = 2-acetylthiophene acetoylhydrazone (ATAH), 2-acetylthiophene benzoylhydrazone (ATBH)} have been investigated on the basis of elemental analysis, molar conductivity measurements, magnetic susceptibil

Solvent-free microwave assisted synthesis and corrosion inhibition study of a series of hydrazones derived from thiophene derivatives: Experimental, surface and theoretical study

A series of thiophene hydrazones namely acetyl thiophene benzohydrazide (ATBH), acetyl thiophene amino benzohydrazide (ATABH), propanoyl thiophene benzohydrazide (PTBH) and propanoyl thiophene amino benzohydrazide (PTABH) were synthesized by conventional

Stereoselective, solvent free, highly efficient synthesis of aldo- and keto-: N -acylhydrazones applying grindstone chemistry

A mild and efficient synthesis of N-acylhydrazones has been developed, applying a simple grindstone procedure, leading to a library of 51 examples exhibiting a broad variety of structural features, 21 of them described for the first time in this paper. Th

Acylhydrazones as Widely Tunable Photoswitches

Molecular photoswitches have attracted much attention in biological and materials contexts. Despite the fact that existing classes of these highly interesting functional molecules have been heavily investigated and optimized, distinct obstacles and inherent limitations remain. Considerable synthetic efforts and complex structure-property relationships render the development and exploitation of new photoswitch families difficult. Here, we focus our attention on acylhydrazones: a novel, yet underexploited class of photochromic molecules based on the imine structural motif. We optimized the synthesis of these potent photoswitches and prepared a library of over 40 compounds, bearing different substituents in all four crucial positions of the backbone fragment, and conducted a systematic study of their photochromic properties as a function of structural variation. This modular family of organic photoswitches offers a unique combination of properties and the compounds are easily prepared on large scales within hours, through an atom-economic synthesis, from commercially available starting materials. During our thorough spectroscopic investigations, we identified photoswitches covering a wide range of thermal half-lives of their (Z)-isomers, from short-lived T-type to thermally stable P-type derivatives. By proper substitution, excellent band separation between the absorbance maxima of (E)- and (Z)-isomers in the UV or visible region could be achieved. Our library furthermore includes notable examples of rare negative photochromic systems, and we show that acylhydrazones are highly fatigue resistant and exhibit good quantum yields.

Mild, Stereoselective, and Highly Efficient Synthesis of N-Acylhydrazones Mediated by CeCl3·7H2O in a Broad Range of Solvents

In a mild and practical approach, hydrazides and aldehydes underwent condensation reactions that were mediated by cerium(III) chloride to be rapidly converted into N-acylhydrazones. This method uses a minimal catalytic amount of cerium(III), is stereosele

Synthesis, crystal structures and use in ethylene oligomerization catalysis of novel mono- and dinuclear nickel complexes supported by (E)-N′-(1- (thiophen-2-yl)ethylidene)benzohydrazide ligand

The coordination chemistry of NiII supported by (E)-N′-(1-(thiophen-2-yl)ethylidene)benzohydrazide ligand (HL) is reported and discussed. The crystal structure of ligand HL has been determined as well as those of three new NiII complexes (Ni(HL)2Br 2, NiL2 and μ-aquo-Ni2L4). The pseudo-octahedral bis(chelate) Ni(II) complex 2 (NiL2), in which unexpected and singular Ni...S interaction is observed, was evaluated as catalyst for the oligomerization of ethylene and found to provide ethylene dimers and trimers as primary products with a turnover frequency (TOF) of 31 200 mol of C2H4 per mol. of Ni and per hour.

Synthesis, structural and corrosion inhibition studies on cobalt(II), nickel(II), copper(II) and zinc(II) complexes with 2-acetylthiophene benzoylhydrazone

Cobalt(II), nickel(II), copper(II) and zinc(II) complexes with 2-acetylthiophene benzoylhydrazone have been synthesized and characterized by elemental analyses, magnetic susceptibility measurements, electronic, IR, NMR and ESR spectral techniques. The molecular structures of ligand and its copper(II) complex have been determined by single crystal X-ray diffraction technique. The Cu(II) complex possesses a CuN2O2 chromophore with a considerable delocalization of charge. The structure of the complex is stabilized by intermolecular π-π stacking and C-H...π interactions. Hatbh acts as a monobasic bidentate ligand in all the complexes bonding through a deprotonated C-O- and >CN groups. Electronic spectral studies indicate an octahedral geometry for the Ni(II) complex while square planar geometry for the Co(II) and Cu(II) complexes. ESR spectrum of the Cu(II) complex exhibits a square planar geometry in solid and in DMSO solution. The trend g|| > g⊥ > 2.0023 indicates the presence of an unpaired electron in the dx2-y2 orbital of Cu(II). The electro-chemical study of Cu(II) complex reveals a metal based reversible redox behavior. The Ni(II) complex shows exothermic multi-step decomposition pattern of the bonded ligand. The ligand and its most of the metal complexes show appreciable corrosion inhibition properties for mild steel in 1 M HCl medium. [Co(atbh)2] complex exhibited the greatest impact on corrosion inhibition among the other compounds.

Fast synthesis of N-acylhydrazones employing a microwave assisted neat protocol

A variety of N-acylhydrazones were synthesized under microwave irradiation within 2.5-10 min, starting from benzo, salicyloyl, and isonicotinic hydrazides. The protocol developed employs microwave irradiation in the absence of solvents and catalysts, lead

Enantioselective Allylation of Ketone-Derived Benzoylhydrazones: Practical Synthesis of Tertiary Carbinamines

A highly practical method for the enantioselective allylation of ketone-derived benzoylhydrazones has been developed. The previously reported strained silacycle reagent 1 reacts with a wide variety of benzoylhydrazones to give the hydrazide products with