113890-95-2Relevant academic research and scientific papers
Rapid and scalable synthesis of chiral porphyrin cage compounds
Gilissen, Pieter J.,Swartjes, Anne,Spierenburg, Bram,Bruekers, Jeroen P.J.,Tinnemans, Paul,White, Paul B.,Rutjes, Floris P.J.T.,Nolte, Roeland J.M.,Elemans, Johannes A.A.W.
, p. 4640 - 4647 (2019)
An improved and scalable synthetic route to chiral porphyrin cage compounds, which will be used as catalytic machines for the encoding of information into polymers, has been developed. The porphyrin cage was made chiral by introducing one or two nitro gro
A four-phenyl porphine production method (by machine translation)
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Paragraph 0059-0062; 0095-0102, (2020/02/07)
The invention discloses a production method for tetraphenyl porphin. The production method includes the steps that 1, pyrrole and aromatic aldehyde are prepared into a mixed solution for standby application; 2, solvent is added into a polymerization reactor, the pressure of the polymerization reactor is maintained at 1-5 atm, the mixed solution obtained in the step 1 starts to be dripped to start a polymerization reaction, after the reaction is finished, reaction products are cooled to normal temperature, and filter liquor and a filter cake are obtained through filtration; 3, the filter cake obtained in the step 2 and propionic acid are added into an oxidation reactor, oxygen-containing gas is introduced to carry out an oxidation reaction, cooling is carried out after oxidation is finished, a solid and filter liquor are obtained through filtration, and the solid is washed and dried to obtain the tetraphenyl porphin. The production method has the advantages of being high in yield, safe and environmentally friendly, separation and purification are easy, and the production quality is stable.
A four-phenyl porphine preparation method
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Paragraph 0060; 0103-0109, (2018/03/26)
The invention discloses a preparation method of meso-tetraphenylchlorin. The preparation method comprises the steps that 1, a mixed solution of pyrrole and aromatic aldehyde is prepared for standby; 2, a solvent is added into a polymerization reactor, nitrogen displacement is conducted till the concentration of tail oxygen is lower than 1%, the solvent is heated to backflow, the mixed solution obtained in the first step starts to be dropwise added, a reaction is started, after the mixed solution is dropwise added completely, the reaction is continuously conducted for 0.05 h to 0.5 h, and then the reaction is stopped; 3, oxygen-containing gas with the oxygen volume fraction ranging from 5% to 100% is fed into the polymerization reactor for oxidation, cooling is conducted after the oxidation is completed, filtration is conducted to obtain a filter cake and filtrate, and a product is obtained after the filter cake is washed and dried. The preparation method of the meso-tetraphenylchlorin has the advantages that the yield is high, safety and environmental protection are achieved, separation and purification are easy, and the product quality is stable.
Microwave-assisted synthesis of a new series of resorcin[4]arene Cavitand-capped porphyrin capsules
McKay, Michael G.,Cwele, Thandanani,Friedrich, Holger B.,Maguire, Glenn E. M.
supporting information; experimental part, p. 3958 - 3968 (2009/12/06)
Capsule-shaped molecular receptors are fundamental to the modeling of biological host-guest interactions such as those characteristic of enzymatic processes. Among the more versatile and effective synthetic receptors are the hemicarcerand-type hosts. Herein we report the synthesis of six novel resorcin[4]arene cavitand-capped porphyrin capsules, in a new series of molecular capsules modeled on the classical hemicarcerands initially reported by Cram and co-workers. In the first reported instance of its utilisation in the preparation of supramolecularly-capped porphyrin host molecules, microwave (MW) irradiation was used (in conjunction with Adler conditions) in order to form the porphyrin cap in situ. Additionally, the yields obtained via these conditions exhibited a significant improvement, relative to the traditional refluxing protocol hitherto reported. Capsules 20-25 are indefinitely stable, and we observed that 22 and 25 possess the smallest rigidified cavities yet reported for resorcin[4]arene cavitand-capped porphyrin host molecules.
Manganese porphyrin hosts as epoxidation catalysts - Activity and stability control by axial ligand effects
Elemans, Johannes A. A. W.,Bijsterveld, Edward J. A.,Rowan, Alan E.,Nolte, Roeland J. M.
, p. 751 - 757 (2008/02/07)
The catalytic performance of a cavity-containing [(porphyrin)Mn] in the epoxidation of alkenes is described. Inside the catalyst cavity, nitrogen-containing axial ligands can be bound to the porphyrin metal with high association constants, resulting in strong activation of the catalyst in the presence of only one equivalent of the ligand. Complexation of a sterically demanding ligand to the outside of the cavity-containing catalyst can prevent catalyst decomposition through the formation of ν-oxo dimers. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
Porphyrin compounds for imaging tissue oxygen
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Page column 21, (2010/01/31)
Methods and compounds for the measurement in vivo of oxygen in living tissue. The compounds preferably comprise a substituted porphyrin which is soluble in aqueous solution which is capable of absorbing an amount of energy and subsequently releasing the e
Asymmetric cycloaddition reactions
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Page column 57-58, (2010/01/31)
The present invention relates to a process for stereoselective cycloaddition reactions which generally comprises a cycloaddition reaction between a pair of substrates, each either chiral or prochiral, that contain reactive π-systems, in the presence of a non-racemic chiral catalyst, to produce a stereoisomerically enriched product. The present invention also relates to novel asymmetric catalyst complexes comprising a metal and an asymmetric tridentate ligand.
Synthesis of (hydroxyphenyl)porphyrins
Syrbu,Semeikin
, p. 1236 - 1239 (2007/10/03)
Demethylation process for (methoxyphenyl)porphyrins was improved by using BBr3 as demethylating agent. A series of (hydroxyphenyl)porphyrins was prepared.
Porphyrin synthesis in surfactant solution: Multicomponent assembly in micelles
Bonar-Law, Richard P.
, p. 3623 - 3634 (2007/10/03)
A synthesis of meso-substituted porphyrins in anionic sodium dodecyl sulfate micelles has been developed. Polar, functionalized aromatic aldehydes condense reversibly with pyrrole in the micellar phase. Oxidation of the porphyrinogen then provides functionalized porphyrins in yields of 10-48%. Hydrophobic aldehydes condense irreversibly to give low yields at practical substrate concentrations. Synthesis in D2O solution results in per-β-deuterated porphyrins. A two-phase model is used to rationalize the dependence of porphyrin yield on reactant and surfactant concentration. Micelles are viewed as potential wells which promote porphyrinogen assembly by binding products more tightly than reactants.
Synthesis of porphyrins with pendant arms: Participation of the ancillary ligands to the complexation process in proteic medium
Latouche,Latouche, Celine,Pereyre,Pereyre, Michel,Verlhac,Verlhac, Jean-Baptiste,Mauclaire,Mauclaire, Laurent,Saccavini,Saccavini, Jean-Claude
, p. 1665 - 1666 (2007/10/02)
Ortho substituted porphyrins are able to complex copper (+II) in a neutral aqueous medium containing an excess bovine albumine.
