113893-08-6

Usage

Uses

Used in Pharmaceutical Industry:
Benzothiophene-3-boronic acid is used as a synthetic intermediate for the preparation of thienyl-substituted pyrimidine derivatives. These derivatives exhibit potent antimycobacterial properties, making them valuable in the development of new drugs to combat tuberculosis and other mycobacterial infections.
Used in Chemical Synthesis:
Benzothiophene-3-boronic acid serves as a key building block in the synthesis of 3-O-protected 17-heteroaryl-3-hydroxyestra-1,3,5,16-tetraene-16-carbaldehyde. Benzothiophene-3-boronic acid is further utilized in the preparation of heteroarenes-annelated estranes, which are important in the field of steroid chemistry and have potential applications in medicine.
Used in Catalyst Research:
As a substrate, benzothiophene-3-boronic acid is employed in the study of metal-free coupling reactions of allylic alcohols with heteroaryl boronic acids. These reactions are of interest to chemists due to their potential for developing more sustainable and environmentally friendly synthetic methods.
Used in Coordination Chemistry:
Benzothiophene-3-boronic acid is used as a starting material for the preparation of thienyl-based quinoline and pyridine ligands. These ligands are then used to synthesize platinum complexes, which have applications in various fields, including catalysis and medicinal chemistry.

InChI:InChI=1/C8H7BO2S/c10-9(11)7-5-12-8-4-2-1-3-6(7)8/h1-5,10-11H

Upstream product

• 7342-82-7 3-Bromothianaphthene 
• 5419-55-6 Triisopropyl borate 
• 121-43-7 Trimethyl borate 
• 52732-22-6 isopropoxyboronic acid 
• 1310-73-2 sodium hydroxide 
• 95-15-8 Benzo[b]thiophene 

Downstream Products

• 40306-93-2 3-(3-benzothienyl)benzothiophen 
• 825612-04-2 3-benzo[b]thiophen-3-yl-2-tert-butoxycarbonylamino-3-phenyl-acrylic acid methyl ester 
• 851902-01-7 3-[2-(phenylethynyl)phenyl]-benzothiophene 
• 1011793-97-7 N-[5-(benzo[b]thiophen-3-yl)-3-phenylpyrazin-2-yl]pyridinium aminide 
• 1011793-99-9 N-[5-(benzo[b]thiophen-3-yl)-3-(3,5-dimethylphenyl)pyrazin-2-yl]pyridinium aminide 
• 1082606-05-0 C₂₀H₂₁BO₂S 
• 1180009-60-2 1-acetyl-3-(1-benzothien-3-yl)-5-phenyl-4,5-dihydro-1H-pyrazole 
• 1216771-93-5 4-(2-amino-5-(benzo[b]thiophen-3-yl)pyridin-3-yl)benzamide 
• 1224592-65-7 N-[3-(benzo[b]thiophen-3-yl)-5-phenylpyridin-2-yl]pyridinium aminide 
• 1245947-06-1 (Z)-3-(2-chloro-1-phenoxyvinyl)benzo[b]thiophene 
• 1222999-49-6 9-(benzo[b]thiophen-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one 
• 24257-29-2 3-(4-bromophenyl)-benzo[b]thiophene 

Relevant academic research and scientific papers

Preparation method of benzoheterocyclic-3-boric acid

The invention discloses a preparation method of benzoheterocycle-3-boric acid, and belongs to the technical field of organic boric acid chemistry. The method comprises the following steps: starting from benzoheterocycle, carrying out selective Friedel-Crafts reaction on benzoheterocycle and boron trihalide in the presence of a catalyst, and carrying out hydrolyzing to obtain benzoheterocycle-3-boric acid. According to the method, proper catalysts and reaction conditions are selected, boric acid is obtained after high-selectivity positioning and hydrolysis are conducted on the heterocycle 3 position, and the benzoheterocycle-3-boric acid is obtained after purification by means of the property difference of the boric acid on the 2 position and the boric acid on the 3 position. The method provides a simple synthesis path for benzoheterocycle-3-boric acid, and has the advantages of high yield and easy isomer purification.

1,8-dialkyl-1,4,5,8-naphthalimide compound and preparation method thereof

The invention discloses a 1,8-dialkyl-1,4,5,8-naphthalimide compound. The compound has a structural formula shown in the specification; and in the structural formula, R is a saturated hydrocarbon group at least comprising 6 carbon atoms. The invention als

Synthesis and biological evaluation of thiophene and benzo[b]thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of the 3,4,5-trimethoxystyrene unit

Combretastatin A-4 and isocombretastatin A-4 derivatives having thiophenes or benzo[b]thiophenes instead of the B ring were prepared and evaluated for their in cellulo tubulin polymerization inhibition (TPI) and antiproliferative activities. The presence

NITROGENATED AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE

Provided are a nitrogen-containing aromatic heterocyclic compound useful as an organic semiconductor material and an organic electronic device using this compound. The nitrogen-containing aromatic heterocyclic compound has a fused indole skeleton represented by the following formula (1), the organic semiconductor material contains the said compound, and the organic electronic device uses the said organic semiconductor material. In general formula (1), X is N-A', O, S, or Se; A is an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aromatic hydrocarbon group, or an aromatic heterocyclic group exclusive of a fused heterocycle consisting of 4 rings or more; and R is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aromatic hydrocarbon group, or an aromatic heterocyclic group exclusive of a fused heterocycle consisting of 4 rings or more.

NITROGENATED AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE

Provided are a novel nitrogen-containing aromatic heterocyclic compound and an organic electronic device using the compound. This nitrogen-containing aromatic compound is represented by the general formula (1). Further, the present invention relates to or