113955-30-9

Basic information

• Product Name: (S)-2-((R)-4-Carboxymethyl-5-oxo-2-thiophen-2-yl-4,5,6,7-tetrahydro-[1,4]thiazepin-6-ylamino)-4-phenyl-butyric acid ethyl ester
• CAS NO: 113955-30-9
• Molecular Weight: 474.602
• Mol File: 113955-30-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((R)-4-Carboxymethyl-5-oxo-2-thiophen-2-yl-4,5,6,7-tetrahydro-[1,4]thiazepin-6-ylamino)-4-phenyl-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((R)-4-Carboxymethyl-5-oxo-2-thiophen-2-yl-4,5,6,7-tetrahydro-[1,4]thiazepin-6-ylamino)-4-phenyl-butyric acid ethyl ester(113955-30-9)
• EPA Substance Registry System: (S)-2-((R)-4-Carboxymethyl-5-oxo-2-thiophen-2-yl-4,5,6,7-tetrahydro-[1,4]thiazepin-6-ylamino)-4-phenyl-butyric acid ethyl ester(113955-30-9)

Safety Data

• Hazardous Substances Data: 113955-30-9(Hazardous Substances Data)

Upstream product

• 121740-50-9 [(2R,6R)-5-Oxo-2-thiophen-2-yl-6-(trityl-amino)-[1,4]thiazepan-4-yl]-acetic acid tert-butyl ester 
• 121740-51-0 [(R)-5-Oxo-2-thiophen-2-yl-6-(trityl-amino)-6,7-dihydro-5H-[1,4]thiazepin-4-yl]-acetic acid tert-butyl ester 
• 121740-49-6 (2R,6R)-2-Thiophen-2-yl-6-(trityl-amino)-[1,4]thiazepan-5-one 
• 113955-35-4 ((R)-6-Amino-5-oxo-2-thiophen-2-yl-6,7-dihydro-5H-[1,4]thiazepin-4-yl)-acetic acid tert-butyl ester 
• 110221-27-7 (2R,6R)-6-amino-2-thienylperhydrothiazepin-5-one 
• 109010-59-5 (R)-2-<(4-nitrobenzolsulfonyl)oxy>-4-phenylbuttersaeure-ethylester 
• 113955-29-6 (S)-2-((R)-4-tert-Butoxycarbonylmethyl-5-oxo-2-thiophen-2-yl-4,5,6,7-tetrahydro-[1,4]thiazepin-6-ylamino)-4-phenyl-butyric acid ethyl ester 

Downstream Products

• 113955-31-0 (S)-2-((R)-4-Carboxymethyl-5-oxo-2-thiophen-2-yl-4,5,6,7-tetrahydro-[1,4]thiazepin-6-ylamino)-4-phenyl-butyric acid 

Relevant articles and documents

Synthesis of 1,4-Thiazepine Derivatives Having Angiotensin-Converting Enzyme Inhibitory Property

Reduction of (6R)-6-amino-6,7-dihydro-2-thienyl-1,4-thiazepin-5(4H)-one derivatives with Mg-MeOH gave the corresponding perhydrothiazepinones.Protection with trityl group at the 6-amino group gave predominantly the 2S,6R isomer which was converted to the