113964-74-2Relevant academic research and scientific papers
NEUE METHODE ZUR REGIOSPEZIFISCHEN SUBSTITUTION EINIGER REAKTIONSTRAEGER N-HETEROAROMATISCHER RINGSYSTEME
Anders, Ernst,Markus, Fritz
, p. 2675 - 2676 (1987)
N-Trifluoromethanesulfonyl-heteroarylium salts 1 react with phosphanes 2 to give the C4- or C2-substituted products 4 or 5.By means of a similar procedure, bisphosphonium salts 6 and 7 are formed.The reaction of sodium azide (8), and 6 yields the iminophosphorane 10 via the intermediate 9.
Chemistry of Triphenyl-(or Tri-n-butyl)pyridylphosphonium Salts, 1. - Novel Method for the Regioselective Introduction of Phosphonium Groups into N-Heteroaromatic Ring Systems
Anders, Ernst,Markus, Fritz
, p. 113 - 118 (2007/10/02)
N-Triflyl-heteroarylium triflates such as 3b and analogous salts of pyrazine, benzothiazole, and quinoline are transformed by regioselective reactions with phosphanes 4a and b into the title compounds 15a-f or 16, 17, 18a and b, respectively.With the salt 26 this reaction can be repeated to give the bis-cationic species 28a or b.Using the salt 15a as a representative, some aspects of the chemistry of heteroaryltriphenylphosphonium salts are described: Starting with the common precursor 15a, 2-acylated pyridines 21, 4,4'-bipyridines 23, and pyridylcarbinols 25 are accessible besides 28. - Keywords: Phosphonium groups, introduction into N-heteroaromatic rings / Pyridylphosphonium salts, tri-n-butyl- and triphenyl-
