1139705-27-3Relevant academic research and scientific papers
Synthesis of 18F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination
Kwon, Young-Do,Jeon, Min Ho,Park, Nam Kyu,Seo, Jeong Kon,Son, Jeongmin,Ryu, Young Hoon,Hong, Sung You,Chun, Joong-Hyun
supporting information, p. 5511 - 5516 (2020/07/08)
Sulfuryl fluoride gas is a key reagent for SO2F transfer. However, conventional SO2F transfer reactions have limited 18F-radiochemistry translation, due to the inaccessibility of gaseous [18F]SO2F2. Herein, we report the first SO2F2-free synthesis of aryl [18F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced 18F-. The radiochemical yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [18F]fluorosulfate.
Imidazolylsulfonates: Electrophilic partners in cross-coupling reactions
Albaneze-Walker, Jennifer,Raju, Ravinder,Vance, Jennifer A.,Goodman, Andrew J.,Reeder, Michael R.,Liao, Jing,Maust, Mathew T.,Irish, Patrick A.,Espino, Peter,Andrews, David R.
supporting information; experimental part, p. 1463 - 1466 (2009/08/07)
Aryl imidazolylsulfonates participate as electrophilic coupling partners in palladium-mediated cross-coupling reactions. The aryl imidazolylsulfonates display good stability while maintaining good reactivity in a variety of palladium-catalyzed coupling reactions. Imidazolylsulfonates are a practical and economic alternative to triflates.
