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(Z)-Akuammidine, a naturally occurring alkaloid, is derived from the stem bark extracts of the plant Picralima nitida. It has garnered attention for its potential medicinal properties, particularly its antiplasmodial and antinociceptive effects. (Z)-Akuammidine's unique structure and bioactivity make it a subject of interest for pharmaceutical research and development.

113973-31-2

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113973-31-2 Usage

Uses

Used in Pharmaceutical Industry:
(Z)-Akuammidine is used as an antiplasmodial agent for its ability to inhibit the growth of Plasmodium falciparum, the parasite responsible for causing malaria. Its effectiveness in combating this deadly disease highlights its potential as a therapeutic agent in the fight against malaria.
(Z)-Akuammidine is also used as an antinociceptive agent due to its demonstrated ability to alleviate pain. This property suggests its potential use as an analgesic, offering a natural alternative for pain management.
Further research is necessary to fully understand the pharmacological activities and explore additional therapeutic applications of (Z)-Akuammidine, including its potential synergistic effects when combined with other medications or its use in drug delivery systems to enhance bioavailability and therapeutic outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 113973-31-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,9,7 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 113973-31:
(8*1)+(7*1)+(6*3)+(5*9)+(4*7)+(3*3)+(2*3)+(1*1)=122
122 % 10 = 2
So 113973-31-2 is a valid CAS Registry Number.

113973-31-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl (15α,16S,19Z)-16-(hydroxymethyl)sarpagan-17-oate

1.2 Other means of identification

Product number -
Other names diphenylphosphinated

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:113973-31-2 SDS

113973-31-2Upstream product

113973-31-2Relevant academic research and scientific papers

CHARACTERISTICS OF VELLOSIMINE REDUCTASE, A SPECIFIC ENZYME INVOLVED IN THE BIOSYNTHESIS OF THE RAUWOLFIA ALKALOID SARPAGINE

Pfitzner, Artur,Krausch, Brigitte,Stoeckigt, Joachim

, p. 1691 - 1700 (2007/10/02)

A plant enzyme - vellosimine reductase - has been isolated from Rauwolfia cell suspension cultures.This new enzyme has been purified (110-fold) and characterized.The reductase is a specific enzyme of the sarpagine pathway catalyzing the NADPH dependent conversion of vellosimine into 10-deoxysarpagine.The latter alkaloid is the immediate biogenetic precursor of sarpagine as shown by its high in vivo incorporation rate (86percent) into sarpagine.

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