113984-77-3

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 459-56-3 4-fluorobenzylic alcohol 
• 121-43-7 Trimethyl borate 
• 113984-76-2 1-(tert-butyldimethylsilyloxymethyl)-4-fluorobenzene 

Downstream Products

• 909854-04-2 tert-butyl-(3,5-diethoxy-4-fluoro-benzyloxy)-dimethyl-silane 
• 909854-05-3 (3,5-diethoxy-4-fluoro-phenyl)-methanol 
• 909854-03-1 3,5-Diethoxy-4-fluoro-benzaldehyde 
• 113984-78-4 2-(tert-butyl-dimethyl-silanyloxy)-4-(tert-butyl-dimethyl-silanyloxymethyl)-1-fluoro-benzene 
• 132303-48-1 (5,7-Bis-benzyloxy-6-fluoro-1H-indol-3-ylmethyl)-trimethyl-ammonium; iodide 
• 132303-38-9 5,7-Bis-benzyloxy-6-fluoro-1H-indole-2-carboxylic acid methyl ester 
• 132303-51-6 (5,7-Bis-benzyloxy-6-fluoro-1H-indol-3-yl)-acetonitrile 
• 132303-47-0 (5,7-Bis-benzyloxy-6-fluoro-1H-indol-3-ylmethyl)-dimethyl-amine 
• 132303-54-9 2-(5,7-Bis-benzyloxy-6-fluoro-1H-indol-3-yl)-ethylamine 
• 132303-41-4 5,7-Bis-benzyloxy-6-fluoro-1H-indole-2-carbaldehyde 
• 132303-44-7 5,7-Bis-benzyloxy-6-fluoro-1H-indole 
• 113984-65-9 3-(tert-Butyl-dimethyl-silanyloxy)-4-fluoro-5-hydroxy-benzaldehyde 
• 113984-80-8 3-(tert-Butyl-dimethyl-silanyloxy)-2-fluoro-5-hydroxymethyl-phenol 
• 113984-81-9 3,5-bis(tert-butyldimethylsilyloxy)-1-(tert-butyldimethylsilyloxymethyl)-4-fluorobenzene 

Relevant academic research and scientific papers

Therapeutic Aryl-Amido-Aryl Compounds and Their Use

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as “AAA compounds”), which, inter alia, a

THERAPEUTIC ARYL-AM I DO-ARYL COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as "AAA compounds"), which, inter alia, a

4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES

This invention relates to 4,4-disubstituted piperidine derivatives of the formula (I) wherein A and R1 to R5 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmac

PHENYL, PYRIDINE, QUINOLINE, ISOQUINOLINE, NAPHTHYRIDINE AND PYRAZINE DERIVATIVES

This invention is concerned with compounds of the formulaand pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

PYRIMIDINE AND QUINAZOLINE DERIVATIVES

This invention is concerned with compounds of the formula ( l ) wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

BENZOIMIDAZOLE, TETRAHYDRO-QUINOXALINE, BENZOTRIAZOLE, DIHYDRO-IMIDAZO[4,5-c] PYRIDINONE AND DIHYDRO-ISOINDOLONE DERIVATIVES

This invention relates to compounds of the formula wherein A, R1 to R3 are as defined in the specification and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridine and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES

This invention relates to 4,4-disubstituted piperidine derivatives of the formula wherein A and R1 to R5 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceuti

ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES

This invention relates to compounds of the formula wherein X is O or NR8, Y is CR7 or N, and R1 to R8 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

PYRIDINE, QUINOLINE AND PYRIMIDINE DERIVATIVES

This invention is concerned with compounds of the formula wherein A, R1 to R5 are as defined in the specification and G is a pyridine, quinoline or pyrimidine group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES

This invention is concerned with compounds of the formula (I) wherein X, A, B, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical