113985-16-3Relevant academic research and scientific papers
Synthesis of substituted pyrido[1,2-a]pyrimidines from 2-arylmethylidene-3- fluoroalkyl-3-oxopropionates
Pryadeina,Burgart,Kodess,Saloutin
, p. 2841 - 2845 (2007/10/03)
Cyclocondensation of 2-arylmethylidene-3-fluoroalkyl-oxopropionates with 2-amino-pyridine occurs at both the polyfluoroacylvinyl and alkoxycarbonylvinyl fragments to give alkyl 4-aryl-2-polyfluoroalkyl-4H-pyrido[1,2-a]pyrimidine-3- carboxylates and 4-aryl
Amides parahydroxycinnamiques: synthese et proprietes inhibitrices vis-a-vis de l'alcool coniferylique deshydrogenase (CADH)
Duran, H.,Duran, E.,Bakkar, M. Ben,Gorrichon, L.,Grand, C.
, p. 672 - 680 (2007/10/02)
Parahydroxycinnamoyl amides are easily prepared from the lithioamines and the iminium salts of alkylated acids.Depending on the amine nucleophilic character, the yields are satisfactory with the aminopyridine derivatives, good for a natural product as the N-feruloyltryptamine 10.A good inactivation effect of the target enzyme CADH is observed with the aminopyridine derivatives, in particular with the N-feruloyl 2-amino pyridine 11.
