1139919-47-3Relevant academic research and scientific papers
Regioselective and stereoselective cyclizations of chloropolyols in water: Rapid synthesis of hydroxytetrahydrofurans
Kang, Baldip,Chang, Stanley,Decker, Shannon,Britton, Robert
supporting information; experimental part, p. 1716 - 1719 (2010/09/05)
A concise, stereoselective synthesis of functionalized tetrahydrofuranols has been developed that involves heating readily available chloropolyols in water. These reactions are operationally straightforward and chemoselective for the formation of tetrahydrofurans, obviating the need for complicated protecting group strategies. The efficiency of this process is demonstrated in a short asymmetric synthesis of the natural product (+)-goniothalesdiol.
Development of a concise and general enantioselective approach to 255-disubstituted-3-hydroxytetrahydrofurans
Kang, Baldip,Mowat, Jeffrey,Pinter, Thomas,Britton, Robert
body text, p. 1717 - 1720 (2009/09/06)
Concise syntheses of 2,5-disubstituted-3-hydroxytetrahydrofurans have been developed that provide access to each configurational isomer of this scaffold from a single aldol adduct. Application of these methods to the rapid preparation of (6S,7S,9S,1QS)- a
