114-26-1

Basic information

• Product Name: 2-Methylethoxyphenyl carbamate
• Synonyms: Boruho 50;Brygou;Dalf Dust;ENT 25,671;IPMC;Invisi-Gard;Mrowkozol;NSC 379584;O-(2-Isopropoxyphenyl) N-methylcarbamate;OMS 33;PHC;PHC (carbamate);PHC 7;Propoxylor;Sendran;Suncide;Tendex;Unden;Unden (pesticide);Unden 50PM;o-IsopropoxyphenylN-methylcarbamate;o-Isopropoxyphenyl methylcarbamate;Carbamicacid, methyl-, o-isopropoxyphenyl ester (8CI);Phenol, 2-(1-methylethoxy)-,methylcarbamate (9CI);Phenol, o-isopropoxy-, methylcarbamate (6CI);2-(1-Methylethoxy)phenyl N-methylcarbamate;2-IsopropoxyphenylN-methylcarbamate;2-(1-Methylethoxy)phenol methylcarbamate
• CAS NO: 114-26-1
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.24
• EINECS: 204-043-8
• Mol File: 114-26-1.mol
• Article Data: 21

Chemical Properties

• Melting Point: 91℃
• Boiling Point: 295.445 °C at 760 mmHg
• Flash Point: 132.481 °C
• Appearance: White to tan crystalline powder
• Density: 1.083 g/cm³
• Vapor Pressure: 0.00153mmHg at 25°C
• Refractive Index: 1.502
• Water Solubility: Slightly soluble. 0.2 g/100 mL
• CAS DataBase Reference: 2-Methylethoxyphenyl carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylethoxyphenyl carbamate(114-26-1)
• EPA Substance Registry System: 2-Methylethoxyphenyl carbamate(114-26-1)

Safety Data

• Hazard Codes: T:Toxic;;
• Statements: R25:; R50/53:
• Safety Statements: S37:; S45:; S60:; S61:
• Hazardous Substances Data: 114-26-1(Hazardous Substances Data)

Usage

General Description

2-Methylethoxyphenyl carbamate is a chemical compound with a variety of potential uses in industries such as manufacturing, pharmaceuticals, and more. As a carbamate, it contains an organic functional group, which is derived from carbamic acid, implying that it may have reactive properties. Information about this specific chemical, including its physical and chemical properties, safety information, potential uses, and effects on health and environment may not be readily available or well-documented as it is potentially less commonly used or researched. Therefore, handling or usage of this compound would require extreme caution until appropriate data is available.

InChI:InChI=1/C11H15NO3/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3/h4-8H,1-3H3,(H,12,13)

Synthetic route

2-Isopropoxyphenol (4812-20-8) + methyl isocyanate (624-83-9) → Propoxur (114-26-1)

Conditions	Yield
With N,N'-dimethylbenzylamine at 60 - 90℃; for 3h; Reagent/catalyst; Temperature;	99%
In Dimethyldisulphide at 20℃; for 1h;

Ethyl N-methylcarbamate (105-40-8) + 2-Isopropoxyphenol (4812-20-8) → Propoxur (114-26-1)

Conditions	Yield
With trichlorophosphate In 1,1-dichloroethane
With trichlorophosphate In 1,1-dichloroethane

Propoxur (114-26-1) + chlorocarbonyl isocyanate (27738-96-1) → C13H14N2O5 (84942-49-4)

Conditions	Yield
In chlorobenzene at 130℃; for 1.5h;	71%

Propoxur (114-26-1) → 2-isopropoxyphenyl(chlorosulfenyl)(methyl)carbamate + 2-isopropoxyphenyl(benzyloxysulfenyl)(methyl)carbamate

Conditions	Yield
With sulphur dichloride; triethylamine; benzyl alcohol In dichloromethane	A 42% B n/a

formaldehyd (50-00-0) + Propoxur (114-26-1) → Chloromethyl-methyl-carbamic acid 2-isopropoxy-phenyl ester (39074-56-1)

Conditions	Yield
With thionyl chloride

Propoxur (114-26-1) → methylamine (74-89-5)

Conditions	Yield
aluminium In water; acetonitrile Product distribution; Irradiation; influence of aluminum foil;;

Propoxur (114-26-1) + butan-1-ol (71-36-3) → 2-isopropoxyphenyl(chlorosulfenyl)(methyl)carbamate

Conditions	Yield
With sulphur dichloride; triethylamine In dichloromethane

Propoxur (114-26-1) → 2-isopropoxyphenyl [[(diethoxyphosphinothioyl)-anilino]thio]methylcarbamate + 2-isopropoxyphenyl [[(diethoxyphosphinothioyl)phenylamino]thio]methylcarbamate (66996-03-0)

Conditions	Yield
In N-methyl-acetamide; O,O-diethyl N-(chlorothio)phenylphosphoramidothioate; diethyl ether

Propoxur (114-26-1) → 2-isopropoxyphenyl[[(diethoxyphosphinothioyl) anilino]thio]methylcarbamate

Conditions	Yield
In N-methyl-acetamide; diethyl ether

Propoxur (114-26-1) → C17H20N2O4

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydroxide / water 2: hydrogenchloride; sodium nitrite / water View Scheme

Propoxur (114-26-1) → C9H11O2(1-)*Na(1+) (60525-41-9)

Conditions	Yield
With sodium hydroxide In water

Propoxur (114-26-1) → C9H11O2(1-) (151334-50-8)

Conditions	Yield
With potassium hydroxide at 20℃; under 760.051 Torr; Electrochemical reaction; Inert atmosphere;

Upstream product

• 4812-20-8 2-Isopropoxyphenol 
• 624-83-9 methyl isocyanate 
• 105-40-8 Ethyl N-methylcarbamate 

Downstream Products

• 84942-49-4 C₁₃H₁₄N₂O₅ 
• 66996-03-0 2-isopropoxyphenyl [[(diethoxyphosphinothioyl)phenylamino]thio]methylcarbamate 
• 151334-50-8 C₉H₁₁O₂^(1-) 
• 60525-41-9 C₉H₁₁O₂^(1-)*Na⁽¹⁺⁾ 
• 38777-13-8 N-nitroso propoxur 
• 4812-20-8 2-Isopropoxyphenol 
• 124-38-9 carbon dioxide 
• 74-89-5 methylamine 
• 39074-56-1 Chloromethyl-methyl-carbamic acid 2-isopropoxy-phenyl ester 

Relevant articles and documents

A preparation method of the propoxur

The invention discloses a method for preparing the propoxur, the preparation method in order to O-isopropoxy phenol and methyl isocyanate as the raw material, under the catalytic action of the catalyst preparation propoxur, wherein the catalyst is N, N - dimethyl benzylamine, N, N - dimethyl cyclohexylamine, N, N - dimethyl aniline in the at least one. Preparation method of this invention has the product content is high, high yield, low impurity content and the like, make the product the propoxur, stable quality, high quality of the propoxur is fully consistent with the market requirements.

One-pot, three-step preparation of alkyl and aryl alkylcarbamates from S-methyl N-alkylthiocarbamates

A general procedure for the synthesis of alkyl and aryl alkylcarbamates starting from the corresponding 5-methyl N-alkylthiocarbamates is described. This procedure consists of three steps that are carried out in a one-pot fashion, without isolating the intermediate N-alkylcarbamoyl chlorides or alkyl isocyanates. All the target products were obtained in high yields (16 examples, average yield 91%). To be noted is the recovery of a co-product of industrial interest, dimethyl disulfide, in a half mole amount for each mole of thiocarbamate, with complete exploitation of the reagent. The alkyl isocyanates, if required, can also be isolated in high yields. Georg Thieme Verlag Stuttgart.

Fluid insecticidal formulations for treatment of parasitic insect larvae by dermal application

The present invention relates to the use of polysiloxanes containing at least one quaternary ammonium group as formulation auxiliary in formulations of larvicidal and/or ovicidal active compounds and to compositions containing a) a larvicidal and/or ovicidal active compound and b) a polysiloxane derivative with at least one quaternary ammonium group per molecule, and, if appropriate, further auxiliaries and carriers.